Expert panelists center discussion on two patient scenarios to review recent updates in the treatment landscape of myelofibrosis.
EP. 1: Identifying the Signs and Symptoms of Myelofibrosis
Expert panelists provide an overview of the signs and symptoms indicative of myelofibrosis and consider factors that help to inform prognostication.
EP. 2: What is the Role of Cytogenetics/Genomics in Myelofibrosis?
Shared insight from a panel of experts on the current state of cytogenetics in myelofibrosis and how it impacts treatment pathways for patients.
EP. 3: Biomarkers in Myelofibrosis: LDH, BMF, and Triple-Negative Disease
Key opinion leaders in myelofibrosis management reflect on the role of biomarkers in informing treatment selection, even for patients with triple-negative disease.
EP. 4: Evolving Role of Transplantation in Myelofibrosis
A comprehensive discussion on the respective role stem cell transplantation has in the treatment armamentarium for myelofibrosis.
EP. 5: Selecting Transplantation Versus Systemic Therapy in Myelofibrosis
Focused discussion on the factors that help to select patients for stem cell transplantation over systemic therapy in the setting of myelofibrosis.
EP. 6: Myelofibrosis Management: Current Treatment Guidelines
Expert panelists share brief insight on the current NCCN guidelines for selecting treatment in patients with myelofibrosis.
EP. 7: Patient Scenario 1: A 72-Year-Old Man With Primary Myelofibrosis
Moving on to review the first patient scenario of primary myelofibrosis, panelists elucidate the decisionmaking process when selecting JAK inhibitor therapy.
EP. 8: Value of JAK Inhibitors in Myelofibrosis Management
A broader overview of the role that JAK inhibitors play in patients with myelofibrosis and how that role has continued to evolve in the current treatment paradigm.
EP. 9: JAK Inhibitors in Patients With Cytopenic Myelofibrosis
A brief discussion on the role that JAK inhibitors play in cytopenic myelofibrosis and how best to optimize care with sequencing and dose adjustment.
EP. 10: Myelofibrosis: Dosing JAK Inhibitors and Managing Adverse Events
Continuing their focus on optimizing JAK inhibitor therapy in myelofibrosis, panelists highlight dosing and adverse event management strategies.
EP. 11: Sequencing of JAK Inhibitors in Patients With Myelofibrosis
In light of the current treatment armamentarium for myelofibrosis, key opinion leaders in the field discuss optimal sequencing of available JAK inhibitors.
EP. 12: Patient Scenario 2: A 68-Year-Old Woman With Anemic MF
Nearing the end of their program, panelists consider a patient with anemic myelofibrosis and optimal treatment strategies in that setting.
EP. 13: Key Takeaways: Optimal Use of JAK Inhibitors in MF and Future Directions in Care
Panelists share key takeaways on management strategies in myelofibrosis and hope for future evolutions in the treatment paradigm.
EP. 14: JAK Inhibitors, Mutations, and Transplantation in Myelofibrosis Management
John O. Mascarenhas, MD, led a panel discussion on myelofibrosis management including the use of JAK inhibitors and transplantation.