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Evolving Treatment Approaches in EGFR- Mutated NSCLC: First-Line Therapies and AE Management

home / frontline-forum / evolving-treatment-approaches-in-egfr-mutated-nsclc-first-line-therapies-and-ae-management

Dr. Husain, MD, discusses how new clinical data from ELCC 2025, including findings from MARIPOSA and FLAURA-2, are redefining first-line treatment and sequencing strategies for EGFR-mutant NSCLC to improve long-term outcomes and CNS control.

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1 expert is featured in this series.

EP. 1: Updated Data from MARIPOSA: ELCC 2025

Hatim Husain, MD
October 8th 2025

Dr. Husain discusses how updated MARIPOSA and FLAURA-2 data highlight the growing role of combination regimens in improving both systemic and CNS outcomes for patients with EGFR-mutant NSCLC.


1 expert is featured in this series.

EP. 2: Current Treatment Approach to Treating EGFR mutant-NSCLC

Hatim Husain, MD
October 8th 2025

Dr. Husain discusses how selecting between FLAURA-2, MARIPOSA, and other frontline regimens requires balancing efficacy, safety, and sequencing considerations to deliver the most personalized care in EGFR-mutant NSCLC.


1 expert is featured in this series.

EP. 3: Sequencing Therapies in EGFR-mutant NSCLC

Hatim Husain, MD
October 8th 2025

Dr. Husain discusses how anticipating resistance mechanisms and tailoring post-progression strategies based on initial therapy are key to optimizing sequencing in EGFR-mutant NSCLC.

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