Considerations for adding immunotherapy to the armamentarium for frontline treatment of extensive-stage small cell lung cancer.
EP. 1: Epidemiology and Clinical Course of SCLC
An overview of the prevalence and prognosis of small cell lung cancer.
EP. 2: Evolution of Therapies for SCLC
Mark Socinski, MD, of AdventHealth Cancer Institute discusses his approach to treating small cell lung cancer and reacts to advances in the treatment of extensive-stage disease.
EP. 3: Treatment Challenges in Extensive-Stage SCLC
A review of current options for management of SCLC and the challenges of treating this population.
EP. 4: Immunotherapy as First-Line Treatment for Extensive-Stage SCLC
The rationale for adding an immunotherapy agent to frontline therapy for extensive-stage small cell lung cancer and considerations for patient selection.
EP. 5: The IMpower133 Trial in Extensive-Stage SCLC
Dr Mark Socinski reviews the IMpower133 trial of first-line chemotherapy plus atezolizumab in extensive-stage small cell lung cancer.
EP. 6: Extensive-Stage SCLC: Implications of IMpower133
Practical implications of the IMpower133 study for providers and patients.
EP. 7: Small Cell Lung Cancer: Risk and Prognosis
Benjamin Levy, MD, of the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, comments on risk factors and the prognosis for patients diagnosed with small cell lung cancer.
EP. 8: Small Cell Lung Cancer: Standard of Care
Dr Benjamin Levy describes common treatment approaches for patients with limited-stage small cell lung cancer and extensive-stage small cell lung cancer.
EP. 9: Extensive-Stage Small Cell Lung Cancer: Gaps in Treatment
An overview of current gaps in treatment for patients with extensive-stage, or metastatic small cell lung cancer.
EP. 10: Immunotherapy for First-Line Extensive-Stage SCLC
A discussion regarding typical response rates to frontline therapy for extensive-stage small cell lung cancer and considerations for incorporating an immunotherapy agent into first-line treatment.
EP. 11: First-Line I-O Plus Chemotherapy for Extensive-Stage SCLC
A review of safety and efficacy data demonstrated by the IMpower133 clinical trial of atezolizumab plus chemotherapy as first-line treatment for extensive-stage small cell lung cancer.
EP. 12: Significance of the IMpower133 Trial in Extensive-Stage SCLC
Dr Benjamin Levy describes how the results of the IMpower133 trial and subsequent FDA approval will impact clinical practice and the outlook for patients with extensive-stage small cell lung cancer.