Cover Story Why so many dead-end phase II trials? Researchers build a 'super' antiandrogen Vantage Point: A new era of hormonal manipulation of prostate ca Sorafenib gets ok for liver cancer DEPARTMENTS News & Analysis CT-related radiation blamed for up to 2% of US cancers RT/temozolomide raises possibility of cure in glioblastoma Focus on Breast Cancer Boost may reduce effects of positive lumpectomy margins Vantage Point: Margins and RT boost: Consider cosmetic results Focus on LungCancer Concomitant CT/RT tops sequential for NSCLC patients Vantage Point: Improved local control provides survival advantage