Fredrik Schjesvold, MD, PhD, Discusses the Potential of Minimal Residual Disease –Directed Treatment for Multiple Myeloma

Video

CancerNetwork® sat down with Fredrik Schjesvold, MD, PhD, at the 2021 International Myeloma Workshop to talk about minimal residual disease and its importance in the treatment of multiple myeloma.

At the 2021 International Myeloma Workshop, CancerNetwork® spoke with Fredrik Schjesvold, MD, PhD, founder and head of the Oslo Myeloma Center, about the potential of minimal residual disease (MRD)–directed treatment in multiple myeloma.

Transcript:

One of the things that is very actively discussed at this meeting is when, how, and if to move on to MRD-directed treatment, using MRD negativity or positivity to decide whether to move on with treatment or not. That’s being discussed on the basis of fairly little data. We don’t have any data from randomized studies saying whether that’s a good idea or not, we will know the prognostic value of MRD. There are several studies going on both in Europe and the [United States] of randomizing patients to standard or MRD-directed therapy. It’s important that we don’t establish an approach to this before we have data from these studies.

Recent Videos
Preliminary phase 2 trial data show durvalumab plus lenalidomide was superior to durvalumab alone in refractory/advanced cutaneous T-cell lymphoma.
4 experts are featured in this series.
4 experts are featured in this series.
Performance status, age, and comorbidities may impact benefit seen with immunotherapy vs chemotherapy in patients with breast cancer.
Developing odronextamab combinations following CAR T-cell therapy failure may help elicit responses in patients with diffuse large B-cell lymphoma.
4 experts are featured in this series.
Cytokine release syndrome was primarily low or intermediate in severity, with no grade 5 instances reported among those with diffuse large B-cell lymphoma.