Ginzburg Discusses Most Interesting Presentations From ASH 2021

Video

At the 2021 ASH Annual Meeting, Yelena Ginzburg, MD, spoke about presentations she found most groundbreaking.

Yelena Ginzburg, MD, an associate professor of Medicine, Hematology and Medical Oncology at Mount Sinai, spoke with CancerNetwork® at the 63rd American Society of Hematology Annual Meeting & Exposition, about which abstracts could potentially change the standard of care for patients with polycythemia vera (PV).

Transcript:

There are many agents that are coming through the pipeline. Ultimately, there’s certainly room for rusfertide as a novel agent that may be paradigm shifting, certainly for low-risk, phlebotomy-requiring patients who often suffer from symptomatic iron deficiency that this agent is able to reverse. The symptoms of both PV and systemic iron deficiency appear to be better with this agent based on statistically significant decreases in symptom scores. Rusfertide is certainly novel and poised to change the paradigm, the toolkit, for what options exist for PV patients.

Recent Videos
Certain bridging therapies and abundant steroid use may complicate the T-cell collection process during CAR T therapy.
Educating community practices on CAR T referral and sequencing treatment strategies may help increase CAR T utilization.
A retrospective study sought to assess CRS and ICANS onset and duration, as well as non-relapse mortality causes in patients infused with CAR T-cell therapies.
A retrospective study sought to assess CRS and ICANS onset and duration, as well as non-relapse mortality causes in patients infused with CAR T-cell therapies.
A retrospective study sought to assess CRS and ICANS onset and duration, as well as non-relapse mortality causes in patients infused with CAR T-cell therapies.
Future meetings may address how immunotherapy, bispecific agents, and CAR T-cell therapies can further impact the AML treatment paradigm.
Treatment with revumenib appeared to demonstrate efficacy among patients with KMT2A-rearranged acute leukemia in the phase 2 AUGMENT-101 study.
Advocacy groups such as Cancer Support Community and the Leukemia & Lymphoma Society may help support patients with CML undergoing treatment.
Data from the REVEAL study affirm elevated white blood cell counts and higher variant allele frequency as risk factors for progression in polycythemia vera.
Additional analyses of patient-reported outcomes and MRD status in the QuANTUM-First trial are also ongoing, says Harry P. Erba, MD, PhD.
Related Content