B. Coiffier

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Cost-Effectiveness of Rituximab in Treatment of Diffuse Large B-Cell Lymphoma

B. Coiffier;J. H. Best;L. F. Omnes;J. C. Hornberger
March 1st 2002

Rituximab (Rituxan), when combined with CHOP (cyclophosphamide [Cytoxan, Neosar], doxorubicin HCl, vincristine [Oncovin], prednisone) chemotherapy (R-CHOP) in the treatment of patients with CD20-positive diffuse large B-cell lymphoma (DLCL), significantly prolongs event-free and overall survival (GELA [Groupe d’Etude des Lymphomes de l’Adulte] LNH 98-5 study). Our objective was to estimate the cost-effectiveness of R-CHOP based on the evidence currently available.

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