Laura Austin, MD

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Cancer Stem Cells: Implications for Cancer Therapy

Shaheenah Dawood, MD;Laura Austin, MD;Massimo Cristofanilli, MD
December 15th 2014

This review will focus on properties of cancer stem cells; will compare and contrast the cancer stem cell model with the clonal evolution model of tumorigenesis; will discuss the role of cancer stem cells in the development of resistance to chemotherapy; and will review the therapeutic implications and challenges of targeting cancer stem cells, with an assessment of the potential such an approach holds for improving outcomes for patients with cancer.

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