Dexamethasone, prednisone induction achieve similar event-free survival in childhood ALL
December 8th 2008Dexamethasone and prednisone were equally effective as induction therapy for children with newly diagnosed acute lymphocytic leukemia in terms of five-year event-free survival, according to a second interim analysis of EORTC Trial 58951.
Sargramostim disappoints in CD20+ follicular lymphoma trial
December 8th 2008Sargramostim (Leukine) paired with a patient-specific immunotherapy mitumprotimut-T (Specifid), failed to reduce time to remission in patients with CD20+ follicular lymphoma following therapy with rituximab (Rituxan), according to the highly anticipated results of a phase III clinical trial.
Rasburicase reduces tumor lysis risk in hematologic malignancies
December 8th 2008Rasburicase (RAS) is superior to allopurinol in adult patients with hematological malignancies whose treatment puts them at high risk for developing tumor lysis syndrome or who have hyperuricemia at baseline, according to a study out of Houston’s M.D. Anderson Cancer Center.