Female AYA Cancer Survivors May Benefit From Increased Physical Activity
The study found that older females with central nervous system tumors had significantly lower vigorous physical activity participation vs their counterparts.
Bevacizumab Biosimilar Approved for Intravenous Use in Solid Tumors
Bevacizumab-nwgd was assessed to be comparable to bevacizumab based on a submission showing pharmacokinetic, efficacy, safety, and immunogenicity data.
Chemoimmunotherapy Elicits Survival Benefit in Older ES-SCLC Population
Real-world data may support a new way to consider follow-up treatment for patients who are older with extensive-stage small cell lung cancer.
FDA OKs Larotrectinib in Adult and Pediatric NTRK+ Tumor Populations
Data from the LOXO-TRK-14001, SCOUT, and NAVIGATE trials support the full approval of larotrectinib in NTRK gene fusion-positive tumors.
PTEG Elicits Encouraging Technical Outcomes in Malignant Bowel Obstruction
Post-operative length of stay ranged from 4 to 9 days for patients who underwent percutaneous transesophageal gastrostomy for malignant bowel obstructions.
FDA Accepts IND Application for ST-001 in Relapsed/Refractory SCLC
Investigators will assess the safety, pharmacology, and maximum tolerated dose of ST-001 in relapsed/refractory SCLC as part of a phase 1a/1b trial.
Auditory Attention Decay Noted Post-Treatment in Pediatric Cerebellar Tumors
Quality of life improvements can be made if clinicians better understand auditory attention decay after cancer treatment in pediatric patients with cerebellar tumors.
Tambiciclib Displays Survival Benefit, Enhanced ORR in AML-MRC
Tambiciclib was well tolerated in patients with acute myeloid leukemia with myelodysplastic-related changes, and no new safety signals were observed.
PROSTOX ultra Reliably Predicts Long-Term Radiation AEs in Prostate Cancer
The phase 3 MIRAGE trial findings show that PROSTOX ultra was validated as a biomarker to predict genitourinary toxicity following SBRT.
Promoting Psychosocial Cancer Care on World Psycho-Oncology Day
The International Psycho-Oncology Society announced the first ever WPOD on April 9, 2025, to bring more focus to psychosocial care in cancer therapy.
Integrating Psycho-Oncology Specialists Into Multidisciplinary Cancer Care
It is crucial that oncologists and other cancer care specialists collaborate with psycho-oncology specialists to optimize patient treatment outcomes.
Elevating Psychosocial Care With The First Ever World Psycho-Oncology Day
World Psycho-Oncology Day is an initiative aimed at spreading awareness and pursuing the further integration of psychosocial care into cancer treatment.
Psychosocial Cancer Care Has Direct Ties to QOL, Emotional Well-Being
Organizations such as ASCO and ESMO recognize the importance of integrating psychosocial care into cancer treatment.
103 Leveraging Digital Technology to Improve Breast Cancer Patients’ Understanding of Treatment Recommendations
Durvalumab Combo Shows Encouraging Preliminary Data in High-Risk UTUC
Combining durvalumab with chemotherapy produced a good safety profile without increasing surgical risk in the phase 2 iNDUCT-GETUG V08 trial.
Neoantigen-Specific TIL/Pembrolizumab Elicit Responses in GI Cancers
A phase 2 study found that treatment with tumor-infiltrating lymphocytes elicited a partial response rate of 15.1% in patients with gastrointestinal cancers.
FDA Approves Nivolumab/Ipilimumab in Adult/Pediatric MSI-H or dMMR CRC
The FDA approved nivolumab with ipilimumab in adult and pediatric patients with CRC based on data from the phase 3 CHECKMATE-8HW trial.
PENELOPE-B Trial Shows Mixed Palbociclib Results in Breast Cancer Subtypes
Palbociclib with endocrine therapy did not improve outcomes in hormone receptor–positive, HER2-negative breast cancer but improved invasive DFS in lobular disease.
Optimizing Radiotherapy QOL for Advanced Prostate Cancer Populations
Focused, high-dose radiotherapy doses may prolong survival and the interval to subsequent therapy for patients with advanced prostate cancer.
Surufatinib/Toripalimab Shows Encouraging Activity in NSCLC and SCLC
Surufatinib/toripalimab elicited an ORR of 57.1% in patients with treatment-naïve NSCLC and 15.8% in patients with pretreated SCLC in a phase 2 trial.
ESMO Develops Molecular Tumor Boards Guidelines to Standardize Practice
The ESMO Precision Oncology Working Group recommendations can serve as guidance to define standards for MTBs to integrate precision oncology into practice.
Mitigating Proton Beam Therapy Disparities for Different Cancer Populations
Data show increasing use of proton therapy overall but widening gaps in populations who have access to this treatment, Curtiland Deville Jr, MD, says.
Considerations for TKI Selection and Sequencing in ALK-Positive NSCLC
Patients with ALK-positive NSCLC not vulnerable to neurological adverse effects or prone to weight issues, might benefit from treatment with lorlatinib.
Once-Weekly Doses of Carfilzomib Show Balanced Benefit in Real-World RRMM
A real-world analysis showed that 56 mg/m2 of carfilzomib once weekly offered many benefits over 56 mg/m2 twice weekly and 70 mg/m2 once weekly in myeloma.
Data Show Underutilization of Appendectomy in Appendix Cancer Population
A lack of guidelines, a loss of follow-up, and out-of-state procedures are all potential reasons for 26% of patients undergoing appendectomy.
Elevating the Quality of Cancer Care Via Cross-Department Collaboration
Experts from Sibley Memorial Hospital discuss how multidisciplinary work has enhanced outcomes such as survival and resource use at their institution.
Belzutifan Improves Disease-Specific Symptoms/QOL vs Everolimus in RCC
Time to deterioration in physical functioning and role functioning was similar among those receiving belzutifan vs everolimus for renal cell carcinoma.
Novel Treatments May Have the Potential to Impact GI Cancer Care
Treatment with KRAS inhibitors may help mitigate a common driver of genetic alteration across a majority of pancreatic cancers.
Making a ‘World of Difference’ Via Multidisciplinary Care in GI, GU Cancers
Various methods of communication ensure that members from radiation oncology, pathology, and other departments are on the same page regarding treatment.
Active Surveillance Shows Noninferior OS vs Surgery in Esophageal Cancer
Postoperative complications and mortality after standard or postponed surgery for esophageal cancer after active surveillance were similar in both groups.