An overview of the design and rationale for the phase 2 BRIDGET study looking at the addition of tucatinib to HER2-directed antibody therapy in breast cancer.
Giredestrant Exhibits DFS Improvement in Early-Stage Breast Cancer
According to the developers, giredestrant is the first oral SERD to display beneficial DFS in early-stage breast cancer in the adjuvant setting.
What Were the Key Presentations at ESMO 2025? Oncology Experts Discuss
Presenting investigators at ESMO Congress 2025 highlight findings from clinical trials assessing novel therapeutics across different disease types.
Sacituzumab Govitecan Misses PFS End Point in Metastatic Breast Cancer
Data from the ASCENT-07 trial show an early trend toward improved overall survival with sacituzumab govitecan vs chemotherapy.
Cardiovascular Considerations in Breast Cancer Treatment and Survivorship
Up-front risk stratification for additional cardiovascular testing may help mitigate cardiovascular toxicities in breast cancer treatment.
Palazestrant Combo Shows Preliminary Activity in ER+/HER2– Breast Cancer
The safety profile of palazestrant plus ribociclib in a phase 1b trial was comparable to prior reports of each individual agent.
How Will the Continued Success of ADCs in Breast Cancer Be Propelled in the Future?
Aditya Bardia, MD, highlights the successes and challenges associated with ADC treatments in breast cancer.