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Evolving Landscape of Glioma: A Focus on IDH-Mutant Gliomas

Video Series

CATNON Trial: Concurrent Versus Adjuvant Temozolomide in Treating WHO Grade 3 Astrocytomas Without 1p/19q Codeletion

How do you approach the use of concurrent versus adjuvant temozolomide in treating WHO grade 3 astrocytomas without 1p/19q codeletion?

Videos

Vinay K. Puduvalli, MD, explores recent advances in glioma classification and treatment, discussing the impact of new WHO guidelines, molecular markers, clinical trials, and emerging therapies like IDH inhibitors on patient care strategies, while identifying persisting challenges and future research priorities in neuro-oncology.

Panelists discuss how the updated WHO classification system for gliomas has impacted their treatment approaches, while also addressing the practical difficulties of integrating these changes into routine clinical care.

Real-World Clinical Practice: Challenges With Glioma Management

Panelists discuss how they tailor treatment strategies for oligodendrogliomas and Grade 2 gliomas based on key clinical and molecular markers, with particular attention to insights from the CODEL trial and RTOG 9802 study.

Treatment Approaches for Patients With Oligodendrogliomas and Grade 2 Gliomas

Panelists discuss how they determine the optimal timing of temozolomide administration - concurrent or adjuvant - for WHO grade 3 astrocytomas lacking 1p/19q codeletion, drawing on evidence from the CATNON trial to inform their decision-making process.

CATNON Trial: Concurrent Versus Adjuvant Temozolomide in Treating WHO Grade 3 Astrocytomas Without 1p/19q Codeletion

EP: 1.Real-World Clinical Practice: Challenges With Glioma Management

EP: 2.Treatment Approaches for Patients With Oligodendrogliomas and Grade 2 Gliomas

EP: 3.CATNON Trial: Concurrent Versus Adjuvant Temozolomide in Treating WHO Grade 3 Astrocytomas Without 1p/19q Codeletion