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FACE-OFF: Team Blue vs Team Purple

Video Series

COMMANDS: Long-Term Analysis, Changes in RBC Transfusion Burden, Hemoglobin Levels and ELEMENTS Trial

Videos

Amer Zeidan, MBBS; Catherine Lai, MD; Bart Scott, MD; Andrew Brunner, MD; Jonathan Abbas, MD; Akriti Jain, MD; Mohamed Hegazi, MD; Somedeb Ball, MBBS; and Salman Fazal, MD, examine critical clinical decisions in myelodysplastic syndrome management, including optimal sequencing of erythropoiesis-stimulating agents vs luspatercept, dosing strategies, and efficacy data from pivotal trials such as MEDALIST, IMerge, and ELEMENT-MDS, which demonstrate improvements in transfusion burden and hemoglobin levels.

Panelists discuss how long-term analysis of the ELEMENTS trial reveals significant improvements in red blood cell (RBC) transfusion burden and hemoglobin levels among study participants.

Panelists discuss how the MEDALIST and IMerge trials provide crucial insights into novel therapeutic approaches for treating myelodysplastic syndromes.

MEDALIST and IMerge Trial Presentation and Discussion

Panelists discuss how clinicians should weigh the decision between initiating treatment with erythropoiesis-stimulating agents (ESAs) vs luspatercept in patients with myelodysplastic syndromes.

Debate: Do We Treat First With ESAs or With Luspatercept? 

Panelists discuss how to optimize luspatercept dosing strategies by evaluating the benefits and risks of starting at maximum dose with downward titration vs initiating at lower doses with upward adjustments.

Do We Start Luspatercept at the Highest Dose and Titrate Down or Start Low and Titrate Up?

CancerNetwork® Face-Off

is a live event hosted by CancerNetwork® in which renowned cancer institutions go head-to-head in a friendly debate on the latest data in a specific therapeutic area. The Face-Off program provides the ideal platform for a meaningful dialogue and data review among fellows and attending junior oncologists, as well as other key stakeholders.

COMMANDS: Long-Term Analysis, Changes in RBC Transfusion Burden, Hemoglobin Levels and ELEMENTS Trial

EP: 1.COMMANDS: Long-Term Analysis, Changes in RBC Transfusion Burden, Hemoglobin Levels and ELEMENTS Trial

EP: 2.MEDALIST and IMerge Trial Presentation and Discussion

EP: 3.Debate: Do We Treat First With ESAs or With Luspatercept?

EP: 4.Do We Start Luspatercept at the Highest Dose and Titrate Down or Start Low and Titrate Up?