Comparing BTK Inhibitors in the Treatment of Relapsed CLL

News
Video

Drs Susan O’Brien and Catherine Coombs describe the design and outcomes of the ELEVATE-RR and ALPINE trials that compare BTK inhibitors in CLL.

CN_AtP_CLL_Seg04_ELEVATE
Current Time 0:00
Duration 0:00
Loaded: 0%
Stream Type LIVE
Remaining Time 0:00
 
1x
    • Chapters
    • descriptions off, selected
    • captions off, selected
      Recent Videos
      Current findings from the phase 1/2 CaDAnCe-101 trial show no predictive factors of improved responses with BGB-16673 in patients with CLL or SLL.
      Novel BTK Degrader Shows Activity in CLL/SLL Regardless of Mutation Status
      More Research Needed to Ascertain Ziftomenib’s Mechanism of Action in AML
      More Research Needed to Ascertain Ziftomenib’s Mechanism of Action in AML
      Both clinicians and patients should have as much information as possible to participate in shared decision-making for CLL care, says Jacob D. Soumerai, MD.
      CLL Workshop Emphasizes Engaging Conversations on Shared Treatment Planning
      Sequencing different treatments in the first 3 lines of therapy represents a challenge in chronic lymphocytic leukemia, according to Deborah Stephens, DO.
      Navigating Treatment Decision-Making Challenges in CLL Management
      Compared with second-generation tyrosine kinase inhibitors, asciminib was better tolerated in patients with chronic myeloid leukemia.
      Asciminib Appears to Benefit All Chronic Myeloid Leukemia Subgroups
      Bulkiness of disease did not appear to impact PFS outcomes with ibrutinib plus venetoclax in the phase 2 CAPTIVATE study.
      Undetected MRD Confers Improved PFS With Ibrutinib Combo in CLL/SLL
      A panel of 3 experts on CML
      Advancing CML Management Towards an Ideal Patient Journey
      A panel of 3 experts on CML
      Ensuring Informed CML Care from Diagnosis Onward
      A panel of 3 experts on CML
      CML Treatment: Scenarios that Necessitate Switching Therapy
      A panel of 3 experts on CML
      When CML Therapy Shifts: Collaborative Approaches to Treatment Changes
      Related Content
      Bexobrutideg Achieves High Objective Response Rate in Heavily Pretreated R/R CLL

      Bexobrutideg Achieves High Objective Response Rate in Heavily Pretreated R/R CLL

      Ashley Chan
      June 18th 2025
      Article

      Bexobrutideg, a novel BTK degrader, demonstrated preliminary clinical activity and a consistent safety profile in patients with relapsed/refractory chronic lymphocytic leukemia.

      Managing Cytokine Release Syndrome in Patients on CAR T-Cell Therapy

      Managing Cytokine Release Syndrome in Patients on CAR T-Cell Therapy

      Elizabeth Shpall, MD
      May 29th 2019
      Podcast

      Ahead of the ASCO Annual Meeting, we discuss the assessment and management of cytokine release syndrome in patients with cancer with Elizabeth Shpall, MD.

      Ponatinib Shows Clinical Benefit Over Imatinib in MRD-Positive Ph+ ALL Post Induction

      Ponatinib Shows Clinical Benefit Over Imatinib in MRD-Positive Ph+ ALL Post Induction

      Chris Ryan
      June 17th 2025
      Article

      Ponatinib extended EFS and PFS in patients with newly diagnosed, Ph-positive acute lymphoblastic leukemia who did not achieve MRD negativity after induction.

      Immunotherapy Approaches in AML

      Immunotherapy Approaches in AML

      Naval Daver, MD
      January 17th 2019
      Podcast

      Cancer Network sat down with Dr. Naval Daver to discuss advancements and discoveries in immunotherapy for AML patients.

      Dasatinib Misses Survival End Points in Core-Binding Factor AML

      Dasatinib Misses Survival End Points in Core-Binding Factor AML

      Ariana Pelosci
      June 14th 2025
      Article

      Compared with standard therapy, dasatinib did not improve efficacy for patients with core-binding factor AML.

      The VIALE-A trial showed high activity with revumenib plus azacitidine and venetoclax for patients with NPM1m/KMT2Ar AML.

      Revumenib Plus Azacitidine/Venetoclax Appears Safe in Older NPM1/KMT2Ar AML

      Ariana Pelosci
      June 12th 2025
      Article

      The VIALE-A trial showed high activity with revumenib plus azacitidine and venetoclax for patients with NPM1m/KMT2Ar AML.