CAR-T Referral Process: Insights from UCSF : Episode 2
Decision Points for Using CAR T-Cell Therapy in Early Lines of Treatment
Panelists discuss how, when considering earlier lines of CAR T-cell therapy for relapsed/refractory multiple myeloma, key institutional factors include patient fitness/age, cytogenetic risk status, prior therapy response duration, and BCMA expression levels. Manufacturing timelines, financial considerations, and center-specific outcomes data also influence timing decisions. For patients receiving early-line CAR T therapy, subsequent treatment options typically focus on novel agent combinations or clinical trials exploring additional cellular therapies, with choices guided by response duration to CAR T and the patient’s individual disease characteristics and treatment goals.
EP: 1.Introduction and CAR-T Therapy in Earlier Lines of Treatment for R/R Multiple Myeloma
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EP: 2.Decision Points for Using CAR T-Cell Therapy in Early Lines of Treatment
EP: 3.Second-Line Treatment for R/R Multiple Myeloma: Who Is the “Right Patient”?
EP: 4.Referral Process for CAR T-Cell Therapy: Initial Contact Through Patient Evaluation and Selection
EP: 5.CAR T-Cell Therapy: CAR T-Cell therapy Process and Bridging Therapy
EP: 6.Care Coordination and Transition Strategies for CAR -T Therapy
EP: 7.CAR -T Therapy in Early Lines of R/R MM: Clinical Scenario Discussion and Key Takeaways
EP: 8.Key Takeaways in CAR-T Therapy for Multiple Myeloma
Video content above is prompted by the following:
- What are the key factors that influence your institution’s decision to utilize CAR T therapy in earlier lines of treatment for relapsed/refractory multiple myeloma?
- If you choose to utilize CAR T in earlier lines of therapy, what might you do next and why?
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