Identifying Patients Appropriate for Front Line Maintenance Therapy in Advanced Ovarian Cancer

Video

Dr. Rebecca Previs talks about when first line maintenance therapy is appropriate and which patients should be presented with this option.

Recent Videos
Oncologists are still working on management strategies for neuropathy; a common adverse effect related to chemotherapeutics for ovarian cancer.
Genetic testing information can be used to risk-stratify ovarian cancer survivors for breast cancer, particularly those with BRCA1 or BRCA2 mutations.
Genetic testing for ovarian cancer may help inform treatment decisions for patients with advanced disease, particularly regarding PARP inhibitor use.
Future findings from a translational analysis of the OVATION-2 trial may corroborate prior clinical data with IMNN-001 in advanced ovarian cancer.
Approximately 10% of patients discontinued treatment with avutometinib/defactinib due to toxicity in the phase 2 RAMP 201 trial.
Response rates appeared to be higher with avutometinib plus defactinib vs avutometinib alone in the phase 2 RAMP 201 study.
Patients who respond to avutometinib/defactinib may be maintained on treatment for long periods of time, says Rachel N. Grisham, MD.
Findings from the OVARIO study show that patients with HRR–deficient and BRCA-mutated disease benefitted the most from niraparib/bevacizumab maintenance.
Related Content
IMNN-001 exhibits prolonged favorable safety among patients with advanced newly diagnosed ovarian cancer.

IMNN-001/Chemo Displays TME Shift in Newly Diagnosed Ovarian Cancer

Roman Fabbricatore
September 23rd 2025
Article

IMNN-001 exhibits prolonged favorable safety among patients with advanced newly diagnosed ovarian cancer.

Low grade serous ovarian cancer, a rare epithelial ovarian cancer subtype, requires differentiated treatment from its high-grade counterpart.

Redefining the Treatment Paradigm in Low Grade Serous Ovarian Cancer

Kathleen N. Moore, MD, MS
March 17th 2025
Podcast

Low grade serous ovarian cancer, a rare epithelial ovarian cancer subtype, requires differentiated treatment from its high-grade counterpart.

Health Canada Approves Mirvetuximab Soravtansine in FRα+ Ovarian Cancer

Health Canada Approves Mirvetuximab Soravtansine in FRα+ Ovarian Cancer

Ariana Pelosci
September 4th 2025
Article

Results from the phase 3 MIRASOL trial led to the approval of mirvetuximab soravtansine for patients with FRα+ ovarian cancer.

Target Folate Receptor Alpha in Ovarian Cancer?

Target Folate Receptor Alpha in Ovarian Cancer?

Dmitriy Zamarin, MD, PhD
September 17th 2018
Podcast

Dr. Dmitriy Zamarin speaks with Cancer Network about the findings of a phase II trial in platinum-resistant ovarian cancer patients.

Additional research on novel targeted therapies may be necessary to address the unmet needs in this high-grade serous ovarian cancer population.

Alpelisib Combo Does Not Extend PFS in High-Grade Serous Ovarian Cancer

Russ Conroy
August 13th 2025
Article

Additional research on novel targeted therapies may be necessary to address the unmet needs in this high-grade serous ovarian cancer population.

Further studying the biology of minimal residual disease may uncover ovarian cancer vulnerabilities and inform more effective therapies.

Data Show MRD in Nearly Half of Ovarian Cancer Population in Remission

Russ Conroy
August 4th 2025
Article

Further studying the biology of minimal residual disease may uncover ovarian cancer vulnerabilities and inform more effective therapies.