Circulating Tumor DNA-based Minimal Residual Disease Detection in Colorectal Cancer Management : Episode 7
Incorporating ctDNA-Based MRD Testing and Study Findings Into Clinical Practice
Medical experts examine how recent data on circulating tumor DNA-based minimal residual disease testing may impact the clinical management and treatment of colorectal cancer.
EP: 1.Overview of colorectal cancer and its management
EP: 2.Background on Colorectal Cancer Screening and its Role in Patient Care
EP: 3.Circulating Tumor DNA Detection Techniques
EP: 4.Describing the Value of ctDNA in Clinical Practice
EP: 5.Clinical study of ctDNA-based MRD detection and INTERCEPT program update
EP: 6.Recent findings from BESPOKE
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EP: 7.Incorporating ctDNA-Based MRD Testing and Study Findings Into Clinical Practice
EP: 8.Key Considerations for Selection of ctDNA Detection Methods
EP: 9.Clinical Utility of ctDNA Testing
EP: 10.Barriers to Implementing ctDNA Testing
EP: 11.ctDNA Testing in a CRC Clinical Scenario
EP: 12.ctDNA to Inform Adjuvant Therapy and the CIRCULATE Trial
EP: 13.Interpreting and Communicating ctDNA Results
EP: 14.Addressing Gaps in ctDNA Testing
EP: 15.Exploring the Future of ctDNA and Novel Treatment Strategies
- Please discuss the clinical implications of these recent data for the utility of ctDNA-based MRD testing in CRC treatment and management
- Are any of these findings practice-changing?
- Are you routinely testing patients after surgery and after adjuvant therapy on the basis of these data?
- What are some barriers to enrollment surrounding MRD testing in CRC for ongoing adjuvant studies (like CIRCULATE)?
- Are patients wanting to escalate or de-escalate treatment?
- How are patients reacting to study testing?
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