Julie Vose, MD, MBA, on the Use of CAR T-Cell Therapy in Lymphomas

Video

Julie Vose, MD, MBA, a professor of internal medicine in the Division of Oncology and Hematology at the University of Nebraska Medical Center discussed the benefits of CAR T-cell for patients with follicular lymphoma.

At the 2021 American Society of Clinical Oncology Annual Meeting, CancerNetwork® spoke with Julie Vose, MD, MBA, a professor of internal medicine in the Division of Oncology and Hematology at the University of Nebraska Medical Center, about the numerous trials that read out at the meeting pertaining to CAR T-cell therapy in patients with hematologic malignancies. Vose discusses the benefit of this therapy for patients with follicular lymphoma in addition to how it may affect patients with other lymphomas.

Transcript:

[One category that really excites me is] the use of CAR T-cells for other types of lymphomas other than diffuse large B-cell. There were a couple of different trials that were presented [at ASCO] looking at CAR T-cells for follicular lymphoma. That has shown some follow up information, and we can see that those specific types of CAR T-cells now can be applied to other types of lymphomas and have some good outcomes. We are looking forward to applying that [technology] to other types of lymphomas, as well as other malignancies.

Recent Videos
Trials at scale can be conducted in middle-income, low-middle-income, and even lower-income countries if you organize a trial ecosystem.
Immunotherapy-based combinations may elicit a synergistic effect that surpasses monotherapy outcomes among patients with muscle-invasive bladder cancer.
For example, you have a belt of certain diseases or genetic disorders that you come across, such as sickle cell disease or thalassemia, that are more prevalent in these areas.
Talent shortages in the manufacturing and administration of cellular therapies are problems that must be addressed at the level of each country.
Administering oral SERD-based regimens may enhance patients’ quality of life when undergoing treatment for ER-positive, HER2-negative breast cancer.
Point-of-care manufacturing, scalable manufacturing, and bringing the cost down [can help].
Gedatolisib-based triplet regimens may be effective among patients with prior endocrine resistance or rapid progression following frontline therapy.
Hosts Manojkumar Bupathi, MD, MS, and Benjamin Garmezy, MD, discuss presentations at ESMO 2025 that may impact bladder, kidney, and prostate cancer care.
Mandating additional immunotherapy infusions may help replenish T cells and enhance tumor penetration for solid tumors, including GI malignancies.
Related Content