Mary M. Pasquinelli, APRN, FNP-BC, on the PLCOm2012 Model for Lung Cancer Screening

According to a study published in the Journal of Thoracic Oncology, the PCLOm2012 model was found to be superior to the United States Preventive Services Task Force (USPSTF) criteria at identifying African American ever-smokers for lung cancer screening.

The PLCOm2012 is a validated logistic regression lung cancer risk prediction model based on data collected from the control arm of the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO), which is a randomized controlled trial studying screening to reduce cancer mortality. The model incorporates 11 predictors, including sociodemographic, medical history, and 4 smoking exposure variables.

“The current study demonstrates that the sensitivity to detect lung cancers overall is lower for the USPSTF criteria than for the PLCOm2012 model at all three risk thresholds studied,” the authors wrote. “Moreover, the USPSTF criteria significantly under-selects African American compared to white ever-smokers.”

In an interview with CancerNetwork®, Mary M. Pasquinelli, APRN, FNP-BC, nurse practitioner in the Divions of Pulmonary, Critical Care, Sleep and Allery at the University of Illinois at Chicago, spoke about the PLCOm2012 model and why the implementation of such a model is necessary for African American patients.

This segment comes from the CancerNetwork® portion of the MJH Life Sciences Medical World News, airing daily on all MJH Life Sciences channels.

Reference:

Pasquinelli MM, Tammemägi MC, Kovitz KL, et al. Risk Prediction Model versus United States Preventive Services Task Force Lung Cancer Screening Eligibility Criteria – Reducing Race Disparities. Journal of Thoracic Oncology. doi: 10.1016/j.jtho.2020.08.006