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Optimizing Care Transitions in Multiple Myeloma: Bridging Academic and Community Practices for Bispecific Antibody Therapy : Episode 7

Navigating the Challenges: Transitioning Patients from Community to Academic Settings in Multiple Myeloma Care

October 25, 2024
By Cesar Rodriguez Valdes, MD
Binod Dhakal, MD, MS
  • Appalanaidu Sasapu MD, FACP
  • Leo Shunyakov, MD

Opinion
Video

Panelists discuss how transitioning patients with multiple myeloma from community to academic settings faces challenges including communication gaps, differences in treatment approaches, patient reluctance, and logistical hurdles.

EP: 1.The Power of Partnership: Enhancing Patient Care in Multiple Myeloma through Academic and Community Physician Collaboration

EP: 2.Fast-Tracking Care: Streamlining Referrals for Quicker Treatment in Multiple Myeloma

EP: 3.Collaborative Care vs. Independent Treatment: Does It Impact Patient Outcomes in Multiple Myeloma?

EP: 4.Overcoming Challenges in Patient Referrals: Handling Reluctance and Navigating Barriers to Academic Care

EP: 5.When Is the Right Time? Navigating Key Moments for Referring Multiple Myeloma Patients to an Academic Center

EP: 6.Identifying and Referring Candidates for Bispecific Therapy: Key Factors in Transitioning from Community to Academic Care

Now Viewing

EP: 7.Navigating the Challenges: Transitioning Patients from Community to Academic Settings in Multiple Myeloma Care

EP: 8.Inside the Academic Approach: How Initial Consultations for Bispecific Therapy Referrals Are Handled

EP: 9.Comparing Dosing and Management of BCMA vs Non-BCMA Bispecific Antibodies

EP: 10.Management of Bispecifc AE’s in the Community Setting of Multiple Myeloma Patients

EP: 11.Criteria for Transitioning Patients from Bispecific Therapy to Community Oncologist Care in Multiple Myeloma

EP: 12.Protocols for Monitoring and Managing Long-Term Complications of Bispecific Therapy in Mutlplie Myeloma

EP: 13.Enhancing Communication Between Academic and Community Oncologists During Referral and Treatment in Multiple Myeloma.

EP: 14.Optimizing Patient Reintegration into Community Care Post-Academic Treatment of Bispecifics in Multiple Myeloma

EP: 15.Unmet Needs and Future Directions for Enhancing Bispecific Therapy Care Transitions in Multiple Myeloma

Video content above is prompted by the following:

  • What are some challenges you are seeing when transitioning from community to academic settings
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"[O]ur analysis supports the clinical efficacy and safety of IsaKd as a first-salvage therapy in a specific, and still existing, subset of [patients with multiple myeloma] who relapse during lenalidomide maintenance following autologous stem cell transplantation," according to the study authors.

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“These findings highlight the critical need to address PEM in the management of [patients with multiple myeloma] with ACHF to mitigate the associated poor clinical outcomes,” according to the study authors.

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Developers designed cemsidomide as an orally bioavailable small molecule degrader that targets IKZF1/3, which drive multiple myeloma and non-Hodgkin lymphoma.

Cemsidomide Combo May Produce Responses in Multiple Myeloma

Russ Conroy
May 8th 2025
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Investigators of the phase 1/2 CFT7455-1101 study have determined cemsidomide at a dose of 100 µg safe for expansion.


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Steven Finkelstein, MD, DABR, FACRO
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"[O]ur analysis supports the clinical efficacy and safety of IsaKd as a first-salvage therapy in a specific, and still existing, subset of [patients with multiple myeloma] who relapse during lenalidomide maintenance following autologous stem cell transplantation," according to the study authors.

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Extramedullary disease was the only factor that correlated with worse progression-free survival per multivariate analysis.


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CCR Scores and Beyond: Precision Strategies for Treatment Intensification in Prostate Cancer

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Alvaro Martinez, MD discusses how emerging genomic risk stratification tools such as the clinical cell-cycle risk (CCR) score are transforming personalized prostate cancer treatment by enabling more nuanced assessments of metastasis risk and treatment intensification strategies beyond traditional NCCN risk groupings.


“These findings highlight the critical need to address PEM in the management of [patients with multiple myeloma] with ACHF to mitigate the associated poor clinical outcomes,” according to the study authors.

Mortality, Adverse Outcome Odds Higher in Multiple Myeloma PEM Population

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Article

Findings indicate a need to address protein-energy malnutrition in the treatment of those who have multiple myeloma with acute congestive heart failure.


Treatment with daratumumab-based combination therapies may drive minimal residual disease conversion rates in patients with newly diagnosed multiple myeloma.

Assessing CD38 Monoclonal Antibody-Based Regimens in NDMM

Roman Fabbricatore
April 27th 2025
Article

Treatment with daratumumab-based combination therapies may drive minimal residual disease conversion rates in patients with newly diagnosed multiple myeloma.

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