The discussion on biomarker testing practices for patients with non–small cell lung cancer turns its focus to the metastatic setting.
FDA Accepts NDA for Zidesamtinib in Pretreated Advanced ROS1+ NSCLC
Zidesamtinib elicited positive activity in patients with advanced ROS1-positive NSCLC who previously received a ROS1 TKI in the phase 1/2 ARROS-1 trial.
Integrating Dato-DXd Into Early-Line EGFR-Mutant NSCLC Management
Jacob Sands, MD, discussed considerations for EGFR-mutant non–small cell lung cancer following the approval of dato-DXd in this disease.
EU Approves Subcutaneous Pembrolizumab in All Approved Indications
The regulatory decision regarding the subcutaneous pembrolizumab formulation is based on results from the phase 3 3475A-D77 trial.
Practice-Changing Lung Cancer Data From the 2025 ASCO Annual Meeting
Stephen Liu, MD; and Joshua Sabari, MD, discuss the most intriguing non–small cell lung cancer and small cell lung cancer breakthroughs from the meeting.
Imneskibart Yields Activity and Responses in Melanoma, NSCLC Cohorts
One patient with metastatic bladder cancer experienced an ongoing metabolic complete response following treatment with aldesleukin/imneskibart.
Novel IL-2 Therapy Combo Yields Initial Responses in Nonsquamous NSCLC
Data from a phase 1a/1b trial show that no patients discontinued STK-012 due to treatment-related adverse effects.