Moaath Mustafa Ali, MD, MPH, reviews data on olverembatinib in patients with heavily pretreated/refractory chronic myeloid leukemia.
Zanubrutinib Therapies Yield Durable Results in High-Risk, Treatment-Naïve CLL/SLL
Results from arms C and D of the phase 3 SEQUOIA trial demonstrated that zanubrutinib alone or in combination with venetoclax yields positive results in CLL/SLL subpopulations.
Evolutions Across NSCLC, Multiple Myeloma, and AML at Georgia Cancer Center
Experts from Georgia Cancer Center highlight ongoing retrospective studies, translational research, and other initiatives across different cancers.
CART19 Yields Promising Efficacy in CNS-Relapsed B-ALL
The 1-year EFS with CART19 was 90% among patients with B-ALL who had 1 or more CNS relapses.
Charting the Evolution of TKIs and Finding the Next Breakthrough in CML
Jorge Cortes, MD, outlines the impact of imatinib in chronic myeloid leukemia and highlights future initiatives in the field.
Zanubrutinib Regimen Sustains PFS Benefit Across CLL/SLL Mutation Statuses
Data from the SEQUOIA trial support the use of zanubrutinib/venetoclax in CLL or SLL regardless of del(17p)/TP53 mutation or IGHV mutational status.
Pirtobrutinib Improves PFS in Treatment-Naive CLL/SLL
Data from the BRUIN-CLL-313 study may support pirtobrutinib as a new potential standard of care for those with untreated CLL or SLL.