Initiating a conversation on patient cases, Divya Gupta, MD, presents the profile of a 76-year-old woman with ROS1+ metastatic non–small cell lung cancer.
Novel IL-2 Therapy Combo Yields Initial Responses in Nonsquamous NSCLC
Data from a phase 1a/1b trial show that no patients discontinued STK-012 due to treatment-related adverse effects.
Integrating Dato-DXd Into Early-Line EGFR-Mutant NSCLC Management
Jacob Sands, MD, discussed considerations for EGFR-mutant non–small cell lung cancer following the approval of dato-DXd in this disease.
Novel TLR Coagonist Combo Shows Responses in Stage IV NSCLC
Phase 2 data showed no dose-limiting toxicities with EIK1001 plus pembrolizumab in patients with advanced non–small cell lung cancer.
Practice-Changing Lung Cancer Data From the 2025 ASCO Annual Meeting
Stephen Liu, MD; and Joshua Sabari, MD, discuss the most intriguing non–small cell lung cancer and small cell lung cancer breakthroughs from the meeting.
Lifileucel Confers Durable Responses in Pretreated Advanced NSCLC Type
Improvements in safety were observed without compromising efficacy after non-myeloablative lymphodepletion was reduced in this NSCLC population.
HER3-DXd Yields Activity in NSCLC, Breast Cancer Brain Metastasis Groups
Data from the phase 2 TUXEDO-3 trial support patritumab deruxtecan as a novel treatment option across different cancer populations with brain metastases.