Research Considerations for ctDNA Testing in Colorectal Cancer

Panelists discuss how research on circulating tumor DNA (ctDNA) testing in colorectal cancer requires careful consideration of standardized collection protocols, analytical validation, clinical utility assessment, integration with existing biomarkers, and longitudinal monitoring to establish its role in personalized treatment decision-making.

EP: 1.The Role of ctDNA in CRC

EP: 2.BESPOKE: Study Design, Efficacy End Points, and Methods

EP: 3.Overview of BESPOKE Patient Characteristics

EP: 4.BESPOKE: Highlighting the Disease-Free Survival by ctDNA Status

EP: 5.BESPOKE: ctDNA Clearance During and After ACT

EP: 6.Role of MRD Status in Treatment Intensification or De-Escalation of Adjuvant Therapy

EP: 7.SWOG 80702: Overview of Study Design, Efficacy End Points, and Patient Characteristics

EP: 8.SWOG 80702: Impressions on the Efficacy Data

EP: 9.Potential Role of Tumor-Informed ctDNA in CRC

EP: 10.Importance of Patient-Centric Approach and Patient Education of ctDNA Testing in CRC and Looking Ahead

EP: 11.The Role of ctDNA Testing in Colorectal Cancer Management: Exploring Its Use Alongside Imaging in Challenging Cases

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EP: 12.Research Considerations for ctDNA Testing in Colorectal Cancer

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