This video reviews the evidence for safe and effective chemotherapy regimens in older patients with breast cancer and highlights the need for geriatric assessment in this population.
In breast cancer trials, most chemotherapy regimens are studied in younger, healthier patients. In practice, many of these regimens have been shown to be too toxic for older women, with higher rates of hospitalization among these patients.
In this video, Hans Wildiers, MD, PhD, of University Hospitals Leuven in Belgium, reviews some of the regimens that are too toxic, highlights one regimen shown to be feasible, and discusses the need for geriatric assessment in this population.
Maintenance Tucatinib Combo Yields PFS Extension in Advanced HER2+ Breast Cancer
December 11th 2025“HER2CLIMB-05 has demonstrated that the addition of tucatinib to HP represents an enhanced frontline maintenance therapy option for patients with HER2-positive metastatic breast cancer,” said Erika Hamilton, MD.