Selecting the Optimal PSMA PET Imaging Agent: Clinical Considerations and Data-Driven Decisions

Opinion
Video

Panelists discuss how medical professionals select PSMA PET tracers based on factors such as diagnostic accuracy, tracer availability, patient-specific considerations, and logistical aspects such as half-life and production facilities. Fluorine-18 (^18F)–labeled tracers, such as ^18F-PSMA-1007, offer logistical advantages due to their longer half-life and higher image resolution, facilitating broader clinical application.

Video content above is prompted by the following:

  • What factors do you consider when selecting a PSMA PET tracer for a particular patient or clinical scenario?
  • When might you opt for F18 vs Ga58, and how do available data inform your decision?
    • Meta-analysis F18 vs G68 (Huang et al. Prostate Cancer. 2023)
    • Do you still see a role for Axumin? If so, in what scenarios?
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