Study Design of the PERSEUS Trial

Opinion
Video

Hematologic oncology specialists provide an overview of the study design of the PERSEUS trial and outline the role of MRD negativity in the treatment of patients with multiple myeloma.

Video content above is prompted by the following question(s):

  • What is minimal residual disease (MRD) and why is achieving MRD negativity significant in the treatment of multiple myeloma?
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“Every patient [with multiple myeloma] should be offered CAR T before they’re offered a bispecific, with some rare exceptions,” said Barry Paul, MD.
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Elucidating nonresponses to bispecific T-cell engagers may be an important research consideration in the multiple myeloma field.
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Shebli Atrash, MD, stated that MRD should be considered carefully as an end point, given potential recurrence despite MRD negativity.
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