Global BulletinAll NewsFDA Approval AlertWomen in Oncology
Expert InterviewsAround the PracticeBetween the LinesFace OffFrom All AnglesMeeting of the MindsOncViewPodcastsTraining AcademyTreatment Algorithms with the Oncology BrothersVideos
Conferences
All JournalsEditorial BoardFor AuthorsYear in Review
Frontline ForumSatellite Sessions
CME/CE
Awareness MonthInteractive ToolsNurse Practitioners/Physician's AssistantsPartnersSponsoredSponsored Media
Career CenterSubscribe
Adverse Effects
Brain Cancer
Breast CancerBreast CancerBreast Cancer
Gastrointestinal CancerGastrointestinal CancerGastrointestinal CancerGastrointestinal CancerGastrointestinal CancerGastrointestinal Cancer
Genitourinary CancersGenitourinary CancersGenitourinary CancersGenitourinary Cancers
Gynecologic CancersGynecologic CancersGynecologic CancersGynecologic Cancers
Head & Neck Cancer
Hematologic OncologyHematologic OncologyHematologic OncologyHematologic Oncology
InfectionInfection
Leukemia
Lung CancerLung CancerLung Cancer
Lymphoma
Neuroendocrine Tumors
Oncology
Pediatric Cancers
Radiation Oncology
Sarcoma
Screening
Skin Cancer & Melanoma
Surgery
Thyroid Cancer
Spotlight -
  • Radiation Oncology
  • Surgery
Adverse Effects
Brain Cancer
Breast CancerBreast CancerBreast Cancer
Gastrointestinal CancerGastrointestinal CancerGastrointestinal CancerGastrointestinal CancerGastrointestinal CancerGastrointestinal Cancer
Genitourinary CancersGenitourinary CancersGenitourinary CancersGenitourinary Cancers
Gynecologic CancersGynecologic CancersGynecologic CancersGynecologic Cancers
Head & Neck Cancer
Hematologic OncologyHematologic OncologyHematologic OncologyHematologic Oncology
InfectionInfection
Leukemia
Lung CancerLung CancerLung Cancer
Lymphoma
Neuroendocrine Tumors
Oncology
Pediatric Cancers
Radiation Oncology
Sarcoma
Screening
Skin Cancer & Melanoma
Surgery
Thyroid Cancer
    • Conferences
    • CME/CE
    • Career Center
    • Subscribe
Advertisement

Study links the risk of ALCL to silicone breast implants

December 2, 2008
Publication
Article
Oncology NEWS InternationalOncology NEWS International Vol 17 No 12
Volume 17
Issue 12

Dutch researchers have found an association between anaplastic large T-cell lymphoma and silicone breast implants.

Dutch researchers have found an association between anaplastic large T-cell lymphoma and silicone breast implants.

Daphne de Jong, MD, PhD, from the pathology department at the Netherlands Cancer Institute in Amsterdam, and colleagues performed an individually matched case-control study that included 11 patients with ALCL, five of whom had received bilateral silicone breast implants one to 23 years before their ALCL diagnosis.

Dr. de Jong’s research group noted the presence of 12 diffuse large B-cell lymphomas, including one T-cell-rich B-cell lymphoma; five Burkitt lymphomas; 10 mucosa-associated lymphoid tissue-type lymphomas; three follicular lymphomas; three peripheral T-cell lymphomas; and two indolent B-cell lymphomas, unclassified.

Dr. de Jong and her colleagues determined that the odds ratio for ALCL associated with silicone breast implants was 18.2 (JAMA 300:2030-2035, 2008).

The researchers said, however, that the absolute risk for developing ALCL due to breast implants is low due to the rare occurrence of ALCL. They also said that more studies are needed to confirm their initial findings.

According to the American Society of Aesthetic Plastic Surgeons, there was a 295% increase in the number of women who had breast augmentation between the years 1997 and 2007.

Articles in this issue

Radiology resident compiles staging database
Study links the risk of ALCL to silicone breast implants
CyBorD combo supports stem cell collection in newly diagnosed multiple myeloma
Clara Bloomfield: Buck conventional wisdom always
New breast cancer program reduces time to treatment
PET/CT for prostate ca influences staging, treatment strategy
Racially-based disparities in ca on the rise, not due to smoking
ProStrakan offers patch to prevent nausea and vomiting
Online tool encourages families to bone up on genetics
Bevacizumab plus copper radiotracer shines as imaging probe
Coverting unresectable to resectable: Data still limited
AACR commits to Love/Avon Army of Women
Voters pass end-of-life measure in Washington state
Brachytherapy improves treatment in augmented women
Marathon effort to support cancer care
Recent Videos
4 experts in this video
4 experts in this video
Historical standards for H3 K27M-mutant diffuse midline glioma treatment may harm healthy central nervous system cells, according to Ashley L. Sumrall, MD.
2 experts are featured in this series.
1 expert is featured in this series.
Related Content
Advertisement

Univariate and multivariate analyses found that increased mortality was associated with the presence of liver metastases at baseline

Atezolizumab Plus Chemo Safe, Efficacious in Broader ES-SCLC Population

Tim Cortese
August 24th 2025
Article

The median overall survival with atezolizumab plus carboplatin and etoposide was 10.6 months in patients with extensive-stage small cell lung cancer.


Beyond the Tumor: Addressing Body Image in Oncology

Beyond the Tumor: Addressing Body Image in Oncology

Daniel C. McFarland, DO;Michelle Fingeret, PhD
August 18th 2025
Podcast

Daniel C. McFarland, DO, and Michelle Fingeret, PhD, discuss the issue of body image in patients with cancer.


Tackling Unmet Needs in Mantle Cell Lymphoma

Tackling Unmet Needs in Mantle Cell Lymphoma

Tycel Phillips, MD
August 24th 2025
Article

Tycel Phillips, MD, highlighted the need for new therapies for patients with MCL who have relapsed on previous lines of treatment.


Navigating the Evolving Second-Line Landscape of Metastatic Urothelial Carcinoma

Navigating the Evolving Second-Line Landscape of Metastatic Urothelial Carcinoma

Manojkumar Bupathi, MD, MS;Benjamin Garmezy, MD
August 14th 2025
Podcast

The latest in first- and second-line therapies for bladder cancer, including trial data, AE management, and the role of molecular testing, were discussed in the latest Oncology Decoded podcast.


Another analysis excluded 7 trials that evaluated neoadjuvant radiation alone in historical cohorts and still found that pCR was not correlated with OS or DFS.

pCR Does Not Correlate With Survival in Rectal Cancer

Tim Cortese
August 23rd 2025
Article

A meta-analysis did not find any correlation between pathologic complete response and overall survival or disease-free survival in patients with rectal cancer.


After the predictive probability of achieving superiority with mFOLFIRINOX or S-IROX was less than 1%, the trial was terminated due to futility.

mFOLFIRINOX/S-IROX Does Not Show Superiority to SOC in Pancreatic Cancer

Roman Fabbricatore
August 22nd 2025
Article

After the predictive probability of achieving superiority with mFOLFIRINOX or S-IROX was less than 1%, the trial was terminated due to futility.

Related Content
Advertisement

Univariate and multivariate analyses found that increased mortality was associated with the presence of liver metastases at baseline

Atezolizumab Plus Chemo Safe, Efficacious in Broader ES-SCLC Population

Tim Cortese
August 24th 2025
Article

The median overall survival with atezolizumab plus carboplatin and etoposide was 10.6 months in patients with extensive-stage small cell lung cancer.


Beyond the Tumor: Addressing Body Image in Oncology

Beyond the Tumor: Addressing Body Image in Oncology

Daniel C. McFarland, DO;Michelle Fingeret, PhD
August 18th 2025
Podcast

Daniel C. McFarland, DO, and Michelle Fingeret, PhD, discuss the issue of body image in patients with cancer.


Tackling Unmet Needs in Mantle Cell Lymphoma

Tackling Unmet Needs in Mantle Cell Lymphoma

Tycel Phillips, MD
August 24th 2025
Article

Tycel Phillips, MD, highlighted the need for new therapies for patients with MCL who have relapsed on previous lines of treatment.


Navigating the Evolving Second-Line Landscape of Metastatic Urothelial Carcinoma

Navigating the Evolving Second-Line Landscape of Metastatic Urothelial Carcinoma

Manojkumar Bupathi, MD, MS;Benjamin Garmezy, MD
August 14th 2025
Podcast

The latest in first- and second-line therapies for bladder cancer, including trial data, AE management, and the role of molecular testing, were discussed in the latest Oncology Decoded podcast.


Another analysis excluded 7 trials that evaluated neoadjuvant radiation alone in historical cohorts and still found that pCR was not correlated with OS or DFS.

pCR Does Not Correlate With Survival in Rectal Cancer

Tim Cortese
August 23rd 2025
Article

A meta-analysis did not find any correlation between pathologic complete response and overall survival or disease-free survival in patients with rectal cancer.


After the predictive probability of achieving superiority with mFOLFIRINOX or S-IROX was less than 1%, the trial was terminated due to futility.

mFOLFIRINOX/S-IROX Does Not Show Superiority to SOC in Pancreatic Cancer

Roman Fabbricatore
August 22nd 2025
Article

After the predictive probability of achieving superiority with mFOLFIRINOX or S-IROX was less than 1%, the trial was terminated due to futility.

Advertisement
About
Advertise
CureToday.com
OncLive.com
OncNursingNews.com
TargetedOnc.com
Editorial
Contact
Terms and Conditions
Privacy
Do Not Sell My Personal Information
Contact Info

2 Commerce Drive
Cranbury, NJ 08512

609-716-7777

© 2025 MJH Life Sciences

All rights reserved.