Transplant-Ineligible NDMM: Updates from CEPHEUS and IMROZ at ASH 2024

Opinion
Video

Panelists discuss recent data updates on transplant-ineligible and deferred newly diagnosed multiple myeloma (NDMM), including findings from the CEPHEUS and IMROZ studies, and explore the clinical significance of minimal residual disease negativity as a prognostic and actionable factor in treatment decision-making for NDMM.

Video content above is prompted by the following:

  • Please comment on recent data updates for transplant-ineligible/deferred newly diagnosed multiple myeloma (NDMM):
  • CEPHEUS study, SubQ Dara-VRd vs VRd in transplant-ineligible NDMM
  • IMROZ study, Isa-VRd vs VRd in TIE/deferred NDMM
  • What is the clinical significance of minimal residual disease (MRD) negativity as a clinical outcome? How do you interpret and integrate MRD negativity into your clinical decision-making? Beyond its prognostic value, what actionable insights does MRD provide in guiding treatment strategies and patient management?
  • Please highlight key insights from MRD analyses in NDMM presented at ASH 2024.
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