Harold J. Burstein, MD, PhD, joins the Oncology Brothers, Rahul Gosain, MD, and Rohit Gosain, MD, to provide clinical insights on treatment practices for patients with early-stage HER2+ breast cancer.
Pyrotinib Combo Sustains Survival Benefits in HER2+ Breast Cancer Trial
Data from the phase 3 PHILA study support pyrotinib plus trastuzumab as a therapeutic strategy in HER2-positive metastatic breast cancer.
What Were the Key Presentations at ESMO 2025? Oncology Experts Discuss
Presenting investigators at ESMO Congress 2025 highlight findings from clinical trials assessing novel therapeutics across different disease types.
RAD51 Test May Improve Patient Selection of Olaparib in BRCA1/2 or PALB2 HER2– Breast Cancer
“This trial supports the value of a functional RAD51-based HRD assessment to refine patient selection for PARP inhibitors,” said Isabel Pimentel, MD.
Cardiovascular Considerations in Breast Cancer Treatment and Survivorship
Up-front risk stratification for additional cardiovascular testing may help mitigate cardiovascular toxicities in breast cancer treatment.
T-DXd Improves iDFS Across HER2+ Early Breast Cancer Subgroups
Subgroup data from the phase 3 DESTINY-Breast05 trial further characterize the clinical benefit of T-DXd over T-DM1 in this breast cancer population.
SABCS 2025: The Top 5 Takeaways for Breast Cancer Research
Sessions from SABCS 2025 detailed potential advances across different immunotherapy, radiation, and surgical modalities in breast cancer care.