RCELONA-Colon cancer patients who received oral capecitabine (Xeloda) after surgery had significantly better 5-year survival rates than those given IV 5-FU/LV chemotherapy, according to a preplanned multivariate analysis of the X-ACT trial data presented at the 2008 World Congress on Gastrointestinal Cancer (Twelves et al: poster 0-033).
RCELONA-Colon cancer patients who received oral capecitabine (Xeloda) after surgery had significantly better 5-year survival rates than those given IV 5-FU/LV chemotherapy, according to a preplanned multivariate analysis of the X-ACT trial data presented at the 2008 World Congress on Gastrointestinal Cancer (Twelves et al: poster 0-033). With a median follow-up of 7 years, 5-year overall survival was 71.4% for capecitabine vs 68.4% for 5-FU/LV (HR 0.86). Capecitabine was associated with fewer adverse events, except for hand-foot syndrome, “which might be a clinical marker of optimal exposure to capecitabine,” the authors said.
How Supportive Care Methods Can Improve Oncology Outcomes
Experts discussed supportive care and why it should be integrated into standard oncology care.