September 19th 2025
Data from the phase 3 3475A-D77 trial support the FDA approval of subcutaneous pembrolizumab across different pediatric and adult solid tumor indications.
Greater regulatory and policy clarity may better optimize clinician use of artificial intelligence in treating patients with cancer.
September 18th 2025
An independent data monitoring committee recommended the continuation of the phase 2 AMPLIFY-7P trial evaluating ELI-002 7P in PDAC in August 2025.
September 17th 2025
Clinical benefit with the investigational agent was reported among 48% of patients with solid tumors at or above the therapeutic dose threshold.
September 10th 2025
Rezatapopt achieved an ORR of 33% in all patients, and an ORR of 43% in patients with ovarian cancer, with 1 confirmed complete response.
A Strong Network of Clinicians Makes Cancer Care More Efficient
Having all the necessary staff together, from medical oncologists to pharmacists, helps deliver the best possible outcomes to patients with cancer.
Fostering Multidisciplinary Care May Reduce Oncologist Workplace Burnout
Joseph C. Landolfi, DO, CPE, and Michele Morrison, MPH, BSHA, RN, discuss how they can use their leadership roles to improve cancer care.
Communication Between Leadership and Clinicians Improves Cancer Care
Leaders of a new cancer center, which is part of JFK University Medical Center, discuss how they can support frontline clinicians.
Workplace Burnout Among Oncologists Has Risen: What Can Be Done?
Results from a recent survey showed that 20% of oncologists planned to reduce their hours in the next 12 months, as workplace burnout among them has increased.
What Does It Mean to Experience Workplace Burnout as an Oncologist?
Workplace burnout in medicine and oncology can lead to stress, exhaustion, fatigue, and a lack of interest in work, according to Eric P. Winer, MD.
FDA Clears IND Application for TROP-2 Targeting ADC in Solid Tumors
Preclinical data showing OBI-902 sustained antitumor activity in solid tumors support the agency’s decision for the IND application.
Oncologists Need to Rely Upon NPs, PAs, and NPPs to Overcome Workforce Problems
Eric P. Winer, MD, said, “[Health care] has a workforce problem, which is part of the reason why we need to embrace nurse practitioners and PAs or APPs.”
Societal Changes, COVID-19 Among Causes of Oncologist Burnout
“Although telehealth is a great thing when used properly, telehealth also puts a barrier between the doctor and the patient,” said Eric P. Winer, MD.
Organ Preservation Noted With Neoadjuvant Dostarlimab in dMMR Tumors
A phase 2 study found a complete clinical response of 82% with neoadjuvant dostarlimab in dMMR solid tumors.
Health Care Professional Research Highlights Barriers to Clinical Trial Diversity
Outlining Strategies for Effectively Implementing Integrative Oncology Care
Findings from clinical trials conducted in recent years demonstrate the benefit of integrative oncology for patients undergoing treatment for cancer.
Navigating the Difficulties of Nutrition During Cancer Care as a Nurse
“Food is powerful, and [patients] need fuel,” said Claudia Aguilar Clancy, RN, FNP-C, about ensuring patients receive the nutrition they require during cancer treatment.
FDA Rejects Breakthrough Designation, Approval for Itolizumab in Acute GVHD
Based on FDA feedback, the developers plan to discontinue the phase 3 EQUATOR study, which evaluated itolizumab in acute graft-versus-host disease.
Genetic Counseling Referrals Rely on Genetic Report Examinations
Suzanne Mahon, DNS, RN, AOCN, AGN-BC, FAAN, stated that it is important to consider a patient’s family medical history when considering genetic counseling.
FDA Clears IND for VS-7375 in KRAS G12D-Mutated Advanced Solid Tumors
The clearance precedes the initiation of a phase 1/2a trial that will evaluate the efficacy and safety of VS-7375 in advanced solid tumors with a KRAS-G12D mutation.
Pharmacist Video Consultations May Reduce Polypharmacy in Cancer Care
Polypharmacy, medication list errors, and drug-drug interactions were all observed in patients with cancer receiving oral anticancer drugs.
CAR T, Targeted Therapies, Others as Treatment Options on the Horizon in NETs
The NETRF lends funding to help discover new and emerging treatment options in neuroendocrine tumors, according to Anna Greene, PhD.
The Greatest Need in NET Research is Funding
Anna Greene, PhD, spoke about how this under-studied disease needs increased funding and more awareness.
Funding is the Greatest Need in Neuroendocrine Tumor Research
Anna Greene, PhD, highlights the NETRF’s role as the largest funder of NET research, their current research funding opportunities, and its commitment to patient support.
Cancer Mortality Shows Long-Term Declines Despite COVID-19 Pandemic
An annual report on the status of cancer showed that, from 2018 to 2022, the cancer death rate fell for every race and ethnicity.
Multicancer Early Detection Test Showed Clinical Benefit, Minimal Distress
Patients with a cancer signal detected via multicancer early detection test demonstrated similar results to those who did not in the PATHFINDER cohort study.
Mindfulness/Activity Program May Ease Anxiety Over Death from Lung Cancer
End-of-life demands card game and mindfulness-based cancer recovery program use may enhance the quality of life for patients with lung cancer.
Classification System May Identify QOL Benefit with Palliative Radiotherapy
Patients with painful lesions who did not undergo treatment with opioids or reirradiation generally had better outcomes than those who did.
Exploring Future Avenues of Growth for Psychosocial Cancer Care
“Psycho-oncology has made remarkable progress; however, there are still critical areas for further development,” Cristiane D. Bergerot, PhD, BS, MS, said.
Most Oncology Nurses Feel Their Post-Pandemic Workload Has Increased
A total of 32% of registered nurses and 29% of infusion nurses reported that educating patients regarding their diseases was challenging.
Female AYA Cancer Survivors May Benefit From Increased Physical Activity
The study found that older females with central nervous system tumors had significantly lower vigorous physical activity participation vs their counterparts.
Bevacizumab Biosimilar Approved for Intravenous Use in Solid Tumors
Bevacizumab-nwgd was assessed to be comparable to bevacizumab based on a submission showing pharmacokinetic, efficacy, safety, and immunogenicity data.
FDA OKs Larotrectinib in Adult and Pediatric NTRK+ Tumor Populations
Data from the LOXO-TRK-14001, SCOUT, and NAVIGATE trials support the full approval of larotrectinib in NTRK gene fusion-positive tumors.
Auditory Attention Decay Noted Post-Treatment in Pediatric Cerebellar Tumors
Quality of life improvements can be made if clinicians better understand auditory attention decay after cancer treatment in pediatric patients with cerebellar tumors.
Promoting Psychosocial Cancer Care on World Psycho-Oncology Day
The International Psycho-Oncology Society announced the first-ever WPOD on April 9, 2025, to bring more focus to psychosocial care in cancer therapy.