September 19th 2025
Data from the phase 3 3475A-D77 trial support the FDA approval of subcutaneous pembrolizumab across different pediatric and adult solid tumor indications.
Greater regulatory and policy clarity may better optimize clinician use of artificial intelligence in treating patients with cancer.
September 18th 2025
An independent data monitoring committee recommended the continuation of the phase 2 AMPLIFY-7P trial evaluating ELI-002 7P in PDAC in August 2025.
September 17th 2025
Clinical benefit with the investigational agent was reported among 48% of patients with solid tumors at or above the therapeutic dose threshold.
September 10th 2025
Rezatapopt achieved an ORR of 33% in all patients, and an ORR of 43% in patients with ovarian cancer, with 1 confirmed complete response.
Integrating Psycho-Oncology Specialists Into Multidisciplinary Cancer Care
It is crucial that oncologists and other cancer care specialists collaborate with psycho-oncology specialists to optimize patient treatment outcomes.
Elevating Psychosocial Care With the First-Ever World Psycho-Oncology Day
World Psycho-Oncology Day is an initiative aimed at spreading awareness and pursuing the further integration of psychosocial care into cancer treatment.
Psychosocial Cancer Care Has Direct Ties to QOL, Emotional Well-Being
Organizations such as ASCO and ESMO recognize the importance of integrating psychosocial care into cancer treatment.
ESMO Develops Molecular Tumor Boards Guidelines to Standardize Practice
The ESMO Precision Oncology Working Group recommendations can serve as guidance to define standards for MTBs to integrate precision oncology into practice.
Telehealth Groups May Improve the Social Lives of Young Cancer Populations
Most patients with cancer who took part in a telehealth group expressed that they liked the members of their group and felt less social isolation.
EU’s CHMP Has Positive Opinion for Subcutaneous Nivolumab in Solid Tumors
Data from the phase 3 CheckMate-67T trial support the CHMP’s recommendation for approving subcutaneous nivolumab across various solid tumor indications.
Solnerstotug Shows Promising Preliminary Data in PD-L1 Resistant Tumors
No dose-limiting toxicities were seen with solnerstotug in patients with PD-L1–resistant tumors, and most adverse effects were grades 1/2 in severity.
ASTCT Women’s History Month Spotlight: Terri Lynn Shigle, PharmD
For Terri Lynn Shigle, PharmD, the field of hematology-oncology is deeply personal. Having lost loved ones to cancer, she was drawn to a career where she could make a meaningful difference in patient care.
ASTCT Women’s History Month Spotlight: Sung-Yun Pai, MD
In celebration of Women’s History Month, ASTCT is proud to highlight the inspiring journeys of women making a profound impact in transplantation and cellular therapy.
Sharing Knowledge is Key for Climate Disaster Preparedness in Cancer Care
Collaboration among different medical and research institutions may help improve quality of care for patients with cancer exposed to climate disasters.
HSCT Recipients Show Sustained Health Challenges Following Transplant
Recipients of hematopoietic stem cell transplantation may benefit from psychosocial interventions and supportive care following their procedure.
Atezolizumab/Chemotherapy May Show Meaningful Activity in Thymic Carcinoma
Phase 2 data may support atezolizumab plus chemotherapy as a treatment option in advanced or recurrent thymic carcinoma.
Investigating the Emergence of Artificial Intelligence on Oncologic Practice
As artificial intelligence has arrived in the oncology field, experts discuss how this new technology can have implications for transforming clinical practice.
Insight Into COVID-19’s Impact On Cancer Care: 5 Years Later
Learn how COVID-19 impacted oncology practice from the uptake of telehealth to delays in screening, with key takeaways from leading oncologists.
New Cohort Approved in Phase 1/2 Trial of TTX-MC138 in Solid Cancers
Based on positive safety data from the third cohort, a safety review committee approved the opening of a fourth cohort as well as more enrollment into the third cohort.
Five-Year Impact of the COVID-19 Pandemic on the Oncology Community
Leading multidisciplinary oncology professionals look back at how the COVID-19 pandemic changed cancer care.
Considerations for Equity and Regulations for AI Tools in Oncology
Testing AI-powered tools globally across diverse patient groups may ensure that they are accurate and consistent for all patients.
Intervention Increases Palliative Cancer Care Consultations/Lowers EOL Care
Celebrating Women in Oncology Through Their Impactful Research and Insights
For International Women's Day, CancerNetwork highlights impactful oncology research on topics from rising health care costs to innovative treatments.
Denosumab Biosimilars Approved by FDA for Previously Referenced Indications
The FDA has approved 2 denosumab biosimilars for all prior approvals for the reference drugs in patients with cancers and osteoporosis.
Identifying Emergent AI Modalities to Optimize Oncology Practice
AI-powered pathology imaging enables a more comprehensive assessment of tumor microenvironments than humans alone could perceive.
Advanced Cancer Population Has Low Use of Supportive Care at End of Life
A retrospective cohort study found that, of Medicare decedents with advanced cancer, 45% experienced potentially aggressive end-of-life care.
NP-G2-044 Elicits Durable Responses, Tumor Control in Advanced Solid Tumors
Phase 2 study results revealed NP-G2-044 plus standard of care anti–PD-1 therapy indicated treatment exhibited responses across at least 7 cancer types.
Sitravatinib Cannot Be Safely Combined With Nivolumab/Ipilimumab in RCC
A phase 1/1b trial found that the triplet combination elicited an ORR of 45.5% and a median PFS of 14.5 months in previously untreated clear cell RCC.
Incentivizing RCC Research Investment Across Lower-Income Countries
Given resource scarcity, developing practice strategies for resource-constrained settings would require aid from commercial and government stakeholders.
Addressing Social Norms Influencing Receipt of Aggressive End-of-Life Care
According to Megan Mullins, PhD, MPH, challenging cultural norms surrounding death and dying may reduce the receipt of low-value end-of-life cancer care.
Identifying and Managing Toxicities From Pembrolizumab Combinations
When pembrolizumab is combined with immunotherapies, the incidence of grade 3 to 5 toxicities increases, especially with anti–CTLA-4 combinations.
Multidisciplinary Approach for AE Management After Pembrolizumab/ICI
“We’ve seen with the initial anti-CTLA-4 ipilimumab experience that, as time went by, we were better at identifying and managing toxicities,” stated Omid Hamad, MD.
Leading Early Conversations About ICD Use in End-of-Life Cancer Care
Earlier and more frequent talks about disabling ICDs with patients receiving end-of-life care and their families may help avoid excessive pain.
The Potential for Improved Processes, Outcomes, and Economics of Health Care
DOGE hopes to solve rampant inefficiencies in US healthcare that contribute to unsustainable costs and a broken system by cutting spending and administrative waste.