Hospice Underuse Linked With Lack of Tailoring for Blood Cancers
Although hematologic oncologists see the value in hospice, their concerns about the adequacy of services for their patients with blood cancers may limit hospice referrals.
Getting Older Cancer Patients on Clinical Trials
This video examines challenges and opportunities in getting older patients with cancer enrolled in clinical trials.
Four-Gene Signature Identified Triple-Negative Breast Cancer Subgroups
The use of a four-gene signature identified a series of subgroups of triple-negative breast cancer, including one subtype that was responsive to platinum-based chemotherapy in the metastatic setting.
16-Gene Recurrence Score for High-Risk RCC Offers Prognostic Value
Analysis from a phase III trial confirmed the prognostic value of a 16-gene recurrence score in patients with high-risk renal cell carcinoma undergoing adjuvant sunitinib therapy.
ctDNA Alterations May Identify Poor Outcomes in Metastatic CRPC
A new study found that patients with mCRPC had higher PSA response with enzalutamide vs abiraterone, but no difference in time to progression, and reported worse outcomes in those with quantifiable ctDNA.
Immunotherapy Yields ‘Dramatic’ Response Rates in Relapsed Mesothelioma
Immunotherapy may represent an effective new treatment approach for relapsed mesothelioma patients, according to a new study.
‘Liquid Biopsy’ Detects DLBCL Gene Copy Number Alterations
Prognostic somatic copy number alterations in diffuse large B-cell lymphoma can be detected and monitored noninvasively using ctDNA from patient plasma.
Psychological Intervention Reduced Fear of Cancer Recurrence
Use of a psychological intervention-Conquer Fear-significantly reduced fear of cancer recurrence in cancer survivors in the first 6 months after treatment.
Protocol Improvements Reduce Health Conditions in Childhood Cancer Survivors
Significant improvements in treatment protocols have reduced the incidence of serious chronic late health effects in survivors of childhood cancer treatment.
Use of SBRT in Treating Pancreatic Cancer
This video highlights the evolution of stereotactic body radiation therapy in the treatment of pancreatic cancer.
FDA Approves Immunotherapy for MSI-High or MMR-Deficient Tumors
The FDA has granted approval to pembrolizumab for pediatric and adult patients with microsatellite instability (MSI)-high or mismatch repair (MMR)-deficient solid tumors.
Treating Locally Advanced Penile Cancer
This video examines the treatment of locally advanced penile cancer and whether an organ-sparing chemoradiotherapy approach might be an option instead of surgery.
Managing Side Effects of Estrogen Deprivation in Breast Cancer Patients
This video examines how to manage the side effects of estrogen deprivation in breast cancer patients, including vaginal dryness and hot flashes.
Late Effects of Estrogen Deprivation in Breast Cancer
This video examines the late effects of estrogen deprivation in both younger and older breast cancer patients, including bone thinning, heart disease, and dementia.
Cytogenetic Abnormalities Do Not Affect Prognosis in Pediatric CML
Chromosomal abnormalities such as a variant t(9;22) translocation do not appear to have significant prognostic impact on children with chronic myeloid leukemia.
Oncologists Reluctant to Give Exercise Recommendations to Cancer Patients
Both oncologists and cancer patients recognize the benefits of physical activity during treatment, but oncologists may feel ill-equipped to give recommendations on exercise, according to a new study.
Adjuvant Oral Chemo in Biliary Tract Cancer Extended Survival
The addition of adjuvant oral chemotherapy with capecitabine extended the overall survival of patients with biliary cancers by a median of 15 months, according to the results of the BILCAP study.
ACA Linked With Earlier Stage Cancer Diagnoses
The implementation of the Affordable Care Act, which increased insurance coverage, was associated with an increase in the diagnosis of several screenable cancers at an earlier stage.
AUA: Prostate Cancer Studies Highlight DNA Repair Gene Involvement
Two new studies presented at the Annual Scientific Meeting of the American Urological Association offer an improved understanding of some genetic underpinnings of prostate cancer.
GnRH Agonist May Protect Ovaries During Early Breast Cancer Treatment
Treatment with the gonadotropin-releasing hormone (GnRH) agonist goserelin can reduce the risk of chemotherapy-induced premature ovarian insufficiency (POI) in women with early breast cancer.
How Do Oncology Professionals Feel About Possible ACA Repeal?
An NCCN survey taken during the period of congressional debate over new federal healthcare legislation, reports how oncology professionals feel about the possible repeal and replacement of the ACA.
Environmental Quality as a Whole Could Impact Cancer Incidence
Exposure to harmful environmental factors was linked with cancer incidence across the United States.
Optimizing Radiotherapy With Immunotherapy in Lung Cancer Treatment
This video examines how the use of radiation therapy in patients on immunotherapy can trigger immunogenic cell death, and reviews some of the challenges related to unwanted immune responses from radiotherapy.
Blended Cognitive Behavior Therapy May Reduce Fear of Cancer Recurrence
Blended cognitive behavior therapy can help reduce the severity of fear of cancer recurrence in survivors, according to a new randomized study.
Inflammation Linked to Cognitive Difficulties in Childhood ALL Survivors
Female survivors of childhood acute lymphoblastic leukemia were at risk for neurocognitive impairment and were more susceptible to the effects of sleep disturbance and fatigue compared with their male counterparts.
Might Chlorhexidine Wipes Reduce CLABSI Risk for Cancer Patients?
Chlorhexidine wipe bathing might help reduce the risk of deadly central line-associated bloodstream infections (CLABSIs) among cancer inpatients, but barriers can complicate implementation efforts.
Role of Nurse Practitioners in Managing Esophageal Cancer, Complications
Nurse practitioners play a central role in helping patients with esophageal cancer understand and manage their disease and treatment complications.
PET Imaging May Predict Early Immunotherapy Response
A noninvasive PET imaging method may serve as a useful predictive biomarker for responses to cancer immunotherapy, according to a new study.
Avoiding Undertreatment, Overtreatment in Geriatric Breast Cancer Patients
This video reviews how to ensure that older breast cancer patients are receiving the most appropriate care and highlights population studies that can help inform individual treatment decisions.
Selecting Safe Chemotherapy Regimens in Older Breast Cancer Patients
This video reviews the evidence for safe and effective chemotherapy regimens in older patients with breast cancer and highlights the need for geriatric assessment in this population.