Frailty in Breast Cancer Patients Does Not Affect Therapy Use
June 19th 2014The CALGB 369901 trial examined how frailty and older age influence the use of adjuvant hormonal therapy for breast cancer and found that while frailty can deter the start of therapy, frail patients who had started on a regimen were not much more likely to discontinue their treatment early.
Fractionation in Breast Cancer Radiotherapy for Conservative Treatment: Are We Really Done Learning?
June 15th 2014There is a need to learn more about the effect of hypofractionation on an individual patient’s breast cancer outcomes and tissue toxicities, based on both biologic and technical variables, so that the treatment decision is not primarily a matter of dollars and cents.
Consider a Single Intraoperative Fraction for Patients Eligible for Hypofractionated Regimens?
June 15th 2014Customized more aggressive treatments should be given to patients with the worst prognosis. For most of the other breast patients, shorter and often milder treatment is also a humble victory in our daily struggle against cancer.
Considering the Cost of Cancer Care in Treatment Decisions
June 11th 2014Words like value, quality, and even cost flowed freely at the ASCO Annual Meeting this year. Along with great excitement about the latest and greatest ways to understand tumor biology and treat cancer patients, there is an increasing recognition that we need to consider whether the things we do are worth it.
The Oncologist’s Duty to Individual Patients vs Duty to Society
June 9th 2014The issue of value in cancer care was a prominent theme at the 2014 ASCO Annual Meeting. A question that inevitably arises in any discussion of value is what the professional and ethical obligations of practicing oncologists are in the current climate of escalating healthcare costs.
Thoracic RT Yields Improved Survival in Extensive-Stage SCLC
June 5th 2014Thoracic radiotherapy along with prophylactic cranial irradiation (PCI) significantly prolonged progression-free and overall survival in patients with extensive-stage small-cell lung cancer, according to results of a new study presented at ASCO.
The Presidential Address: Setting Intentions
June 3rd 2014In his address, Dr. Clifford Hudis proposed the following solutions for achieving social justice in cancer care: creating more private and public resources, addressing disparities in cancer risk and in access to high-quality care, defining “value” in cancer care, and harnessing the new power of information technology.
ASCO: Role of Chemotherapy and Novel Targeted Agents in Prostate Cancer
May 30th 2014As part of our coverage of ASCO's Annual Meeting, we discuss the role of chemotherapy in prostate cancer, as well as study results on novel targeted approaches and agents in development for prostate cancer that will be presented at the meeting.
How to Create Value in Cancer Care
May 16th 2014Take a minute to recall those patients who showed up in the emergency room without your knowledge, or who died 1 week after starting a new treatment, or whom you neglected to enroll in hospice. In each scenario the cost of their care rose without a corresponding increase in value. I’ve listed some behavioral skills that have a chance to prevent unnecessary expense.
Addressing the Common Mystery of the Solitary Pulmonary Nodule
May 15th 2014To ultimately find what we are actually looking for, the invasive malignant nodule in a haystack of benign lesions, new strategies and qualitative and quantitative tools are needed to propel noninvasive evaluation of solitary pulmonary nodules into the 21st century.
Low-Dose Spiral CT Screening and Evaluation of the Solitary Pulmonary Nodule
May 15th 2014The number of lesions detected with low-dose CT, only some of which are early cancers, is so great that algorithms are being developed for more efficient evaluation and management of solitary pulmonary nodules. This article will discuss current tools, approaches, and concerns regarding patient care in this setting.