Use of Advanced Radiation Techniques Increased During Last Year of Life
November 19th 2012Although the number of metastatic cancer patients receiving radiation in the last year of life did not significantly change from 2000 to 2007, a new study has found a shift in radiation use from the simplest radiation treatments to more advanced treatment.
Targeted Therapy: A Sea Change in the Treatment of Cancer
November 16th 2012I see a time in the not too distant future when we’ll define tumors this way. What will our subspecialties be? Rather than a breast clinic or a lung clinic, will we perhaps be attending a “HER2 clinic” or an “mTOR clinic” instead?
Cost of Cancer: There Is More to It Than Containing Chemotherapy Costs
November 15th 2012Including the entire course of care in the efforts to improve quality and contain costs will make the short-term implementation more complex and perhaps controversial. However it will reflect the way that contemporary oncology care is delivered, and will allow for holistic care management and an optimization of cost.
The Cost of Cancer Care: Part II
November 15th 2012In Part II, I focus on ideas and specific programs that may slow the growth of spending while, it is hoped, minimizing the impact on what we all want: sustainable access to high-quality therapy and continued innovation. Finally, I will consider another fundamental question: Is current spending worth it?
An 80-Year-Old Man Presents With Abdominal Pain and Tarry Stools
November 9th 2012In this Stump the Professor video, two fellows test Dr. Marshall's diagnostic skills with a unique case study involving an 80-year-old patient who presents with abdominal pain, bilateral edema, weight loss, and dark, tarry stools.
Study: In Final Months, Older Cancer Patients Pain Under-Addressed
November 8th 2012A new study in the United Kingdom has found an increasing trend in opioid prescribing by general practitioners for cancer pain during a patient’s last 3 months of life. However, data also revealed that older patients had a significantly lower chance of receiving opioids to address cancer pain compared with patients aged 50 years or younger.
ASTRO: Many Terminal Lung Cancer Patients Believe Palliative Radiation Therapy Is a Cure
November 1st 2012A significant portion of patients with incurable lung cancer believe that palliative radiation therapy will cure the disease or at least help them live longer, according to a new study. Only about one-third of patients acknowledged that the treatment was not at all likely to cure their cancer.
Controversies in the Pathology of Thymoma Viewed Through the Prism of Evidence-Based Pathology
October 23rd 2012Thymomas are uncommon neoplasms that have generated considerable controversy among pathologists. The following questions can be used to evaluate the evidence supporting current concepts about the pathology of thymomas and the clinical applicability of those concepts.
Targeted Therapy: Its Status and Promise in Selected Solid Tumors Part I
October 23rd 2012We describe areas where major inroads were initially achieved by targeting angiogenesis and by unraveling pathways in the heterogeneous tumors of mesenchymal origin-spurred by the identification of c-Kit–activating mutations in GIST and the regressions that ensued when tumors harboring these mutations were exposed to the tyrosine kinase inhibitor imatinib (Gleevec).
Adolescents, Young Adults Seek Involvement in End-of-Life Planning
October 22nd 2012Adolescents and young adults want to be more involved in specific aspects of their end-of-life care and found a planning document to aid in those decisions helpful, according to the results of a recently published study.
Communication Key to Parental Decision Making for Children at End of Life
October 9th 2012When facing decisions involving children with cancer at the end of life, three themes drove parental decision making--communication, extending time, and understanding prognosis, according to a recent meta-analysis.