Long-Term Follow-Up of MonumenTAL-1
Larysa J. Sanchez, MD, discusses recent efficacy data presented at EHA 2024 from the long-term follow-up results of the phase 1/2 MonumenTAL-1 study investigating talquetamab in relapsed/refractory multiple myeloma.
EP: 1.Significance of GPRC5D as a Target for R/R MM
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EP: 2.Long-Term Follow-Up of MonumenTAL-1
EP: 3.MonumenTAL-1: Efficacy and Safety Data
EP: 4.Broader Implications and Current Trials of GPRC5D-Targeted Treatments in Relapsed/Refractory Multiple Myeloma
EP: 5.Overview of MonumenTAL-2 and MonumenTAL-3
EP: 6.Evaluating Combination Strategies in R/R MM: TRIMM-2, TRIMM-3, MajesTEC-3
EP: 7.Exploring GPRC5D as an Important Target for Multiple Myeloma
EP: 8.Overview of RedirecTT-1, MagnetisMM-30 and MagnetisMM-5
EP: 9.Implications of Combination Regimens for R/R MM
EP: 10.Overview of Recent Updates in Bispecific Therapy in R/R MM
EP: 11.Impact of T-cell Affinity in Bispecific Therapy in R/R MM
Video content above is prompted by the following:
- Please discuss the efficacy data, focusing on PFS and DOR, presented at EHA 2024 on the long-term follow-up results of the phase 1/2 MonumenTAL-1 study of talquetamab in patients with RRMM.
- What factors might contribute to the longer DOR with Q2W dosing compared to QW dosing in patients naive to prior TCR?
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