MM Treatment: CAR T-Cell Therapy Selection and Insurance Considerations

Opinion
Video

The panel discusses the utilization of CAR T-cell therapy for patients with multiple myeloma, highlighting treatment selection, sequencing, and insurance considerations.

Video content above is prompted by the following questions:

  • How might you consider sequencing therapies for this patient? Please describe how you would approach treating this patient in your practice.
    • What factors impact your decision?
    • How do you incorporate patient preferences and quality of life considerations into the discussion when determining the sequencing of bispecifics and CAR T-cell therapy in R/R MM?
  • Can BCMA-targeting bispecifics be used in patients who have received prior BCMA targeting CAR-T therapies?
    • Might you consider a different target?
  • Might your strategy differ if the patient had received ide-cel instead of cilta-cel?
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4 experts in this video
4 experts in this video
4 experts in this video
4 experts in this video
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Although a similar proportion achieved MRD negativity at the 10 to the –6 power, not enough studies have analyzed MRD at this level for multiple myeloma.
Unique toxicities presented with talquetamab tend to get progressively better as the treatment course continues, according to Prerna Mewawalla, MD.
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