R Tyler Hillman, MD, PhD, on Important Contributors Needed to Treat Ovarian Granulosa Cell Tumors

Video

An expert emphasizes how a big team is needed to properly employ the different therapeutic modalities needed to treat patients with ovarian granulosa cell tumors.

R Tyler Hillman, MD, PhD, of The University of Texas MD Anderson Cancer Center in Houston, spoke with CancerNetwork® at the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting about various clinicians from the multidisciplinary care team necessary to properly treat patients with ovarian granulosa cell tumors.

Transcription:

It takes a big team for these patients because we often employ a variety of different therapeutic modalities. In the recurrent setting, which is predominantly where I see and treat granulosa cell tumors, frequently, we’re using cytoreductive surgery as the mainstay. The key to enhanced recovery from these surgeries involves nutritionists, and floor and [operating room nurses]. And then our advanced practice providers in the clinic provide a lot of the counseling and preoperative preparation to get folks ready for the OR. It’s all especially important because we often combine surgery with adjuvant treatments, so the recovery from surgery impacts how soon we're able to start—whether it's chemotherapy or hormonal therapy—in the adjuvant setting.

Reference

Hillman RT, Lin DI, & Gershenson DM. Assessment of predictive biomarker prevalence in molecularly defined adult-type ovarian granulosa cell tumors. J Clin Oncol 39, 2021 (suppl 15; abstr 5567). 10.1200/JCO.2021.39.15_suppl.5567

Recent Videos
Data from the phase 3 DeLLphi-304 trial at ASCO 2025 revealed a survival advantage with tarlatamab vs chemotherapy in second-line ES-SCLC.
The FDA approval of tarlatamab in SCLC has received much press attention, according to Daniel R. Carrizosa, MD, MS.
The National ICE-T Conference may inspire future collaboration between community and academic oncologists in the management of different cancers.
One of the largest obstacles to tackle in the kidney cancer landscape will be translating the research on rare kidney cancer subtypes into clinical trials.
Long-term toxicities like infections and secondary primary malignancies remain a concern when sequencing novel agents for those with multiple myeloma.
Zanzalitinib exhibited favorable data when evaluated alone or in combination with anti-PD-1 immune checkpoint inhibition in phase 1 RCC trials.
The investigational agent exhibited superior efficacy vs pembrolizumab in patients with lung cancer, suggesting potential efficacy in kidney cancer.
Management of adverse effects and access to cellular therapies among community oncologists represented key points of discussion in multiple myeloma.
“As a community, if we’re looking to help enroll and advocate for patients with rare [kidney cancers], we need to be aware of what is out there,” said A. Ari Hakimi, MD.
Treatment with the dual inhibitor displayed a short half-life and a manageable toxicity profile in patients with clear cell renal cell carcinoma.
Related Content