An overview of the rationale and study design of the INTERCEPT study in patients with colorectal cancer, with a focus on the early key findings.
Zanzalintinib Combo Improves Survival vs Regorafenib in Metastatic CRC
Investigators will submit detailed results from the phase 3 STELLAR-303 trial for presentation at a future medical conference.
Sotorasib Combo Approval May Address Novel Therapy Need in KRAS G12C+ CRC
The approval of sotorasib plus panitumumab is a “welcome step” in KRAS G12C-mutated colorectal cancer, according to Marwan G. Fakih, MD.
Biweekly TAS-102 Reduces Toxicity, Maintains Survival in Metastatic CRC
A retrospective analysis shows that trifluridine/tipiracil with or without bevacizumab given biweekly was favorable in those with colorectal cancer.
Optimizing Metastatic CRC Outcomes Following Fruquintinib Approval
Oncology pharmacist Jagoda Misniakiewicz, PharmD, discusses the potential efficacy and safety profile of fruquintinib in patients with metastatic CRC.
Preoperative Counseling Increases Shared Decision-Making in CRC Surgery
Counseling received prior to colorectal surgery using 3-dimensional–printed anatomic models reduced mean anxiety scores vs conventional counseling.
Novel Therapy Yields Anti-Tumor Activity in KRAS G12C–Mutated CRC
As a single agent or in combination, MK-1084 showed promising efficacy and safety results for patients with KRAS G12C–mutated CRC.