Sam Klempner, MD, joins Rahul Gosain, MD, and Rohit Gosain, MD, to discuss treatment strategies for esophageal, GE junction, and gastric cancers.
TFOX Regimen Enhances Efficacy vs FOLFOX in HER2-Negative Gastric Cancer
The safety profile of TFOX was consistent with data reported in previous studies, and no new safety signals were identified.
Sotorasib Combo Approval May Address Novel Therapy Need in KRAS G12C+ CRC
The approval of sotorasib plus panitumumab is a “welcome step” in KRAS G12C-mutated colorectal cancer, according to Marwan G. Fakih, MD.
Chemoradiation Shows Responses Across Dose Levels in Anal Cancer
Phase 2 data indicate that reduced-dose chemoradiotherapy may be tolerable among patients with early-stage anal cancer.
Educating Patients and Clinicians on End-of-Life Care and Discussions
Kelley A. Rone, DNP, RN, AGNP-c, provides perspective on approaching end-of-life conversations with patients with GI cancers.
Elraglusib Combo Demonstrates OS Benefit in Metastatic Pancreatic Cancer
Phase 2 Actuate-1801 part 3B trial results evaluating elraglusib with GnP in metastatic PDAC will be presented at the 2025 ASCO Annual Meeting.
Atezolizumab/Trastuzumab Plus Chemotherapy Shows Efficacy in Gastric Cancer
Pathological complete response was higher among patients with ERBB2–positive gastric cancer or GEJ adenocarcinoma treated with atezolizumab vs without.