Clinical Improvement Found After Administration of Acalabrutinib for Patients with COVID-19
June 8th 2020A recent study, sparking further trials for investigation, saw improved clinical outcomes and reduced markers of inflammation for patients with severe COVID-19 after treatment with acalabrutinib, a selective BTK inhibitor.
Initiation of Adjuvant Therapy Within 3 Weeks After Surgical Resection of GBM Could Be Detrimental
May 8th 2020Recent data suggests that, while short delays beyond 5 weeks after surgical resection of glioblastoma did not negatively impact survival outcomes, early initiation of chemoradiation before 3 weeks could be detrimental to patients.
Low-Dose Aspirin May Lower Risk of Hepatocellular Carcinoma & Liver-Related Mortality
March 16th 2020A nationwide study found that low-dose aspirin was associated with a significantly lower risk of hepatocellular carcinoma and lower liver-related mortality compared to no aspirin use, without a significantly higher risk of gastrointestinal bleeding.
AYAs with Certain Cancer Types Saw Improvements in 5-Year Mortality Rates
March 11th 2020A study showed that adolescents and young adults with certain types of cancers saw significant improvements in their 5-year mortality rates, while other cancer types saw little to no significant improvement among the same demographic group.
Early Findings Show Promise of CAR NK-Cell Therapy in Leukemia, Lymphoma
February 8th 2020Patients with either relapsed or refractory non-Hodgkin lymphoma or chronic lymphocytic leukemia treated with CAR NK cells had a response without the development of cytokine release syndrome, neurotoxicity, or graft-versus-host disease.
Phase I Trial Aims to Evaluate Cobomarsen in Certain Hematologic Malignancies
February 4th 2020The phase I trial is evaluating cobomarsen in cancers where the disease process appears to be correlated with an increase in miR-155 levels, including adult T-cell leukemia/lymphoma, diffuse large B-cell lymphoma, and chronic lymphocytic leukemia.
Genentech Submits sBLA for Atezolizumab Plus Bevacizumab Combo to Treat Unresectable HCC
January 27th 2020The company’s application is based on results from the phase III IMbrave150 study of the regimen for the treatment of patients with unresectable hepatocellular carcinoma who have not received prior systemic therapy.
Brentuximab Vedotin with Re-induction Chemotherapy Effective, Well Tolerated in AML
January 3rd 2020A phase I study showed brentuximab vedotin combined with a standard chemotherapy regimen of mitoxantrone, etoposide, and cytarabine may be safe and well tolerated in patients with relapsed/refractory acute myeloid leukemia.
Grant Awarded to Address Prescription and Management of Opioids for Patients of Cancer
December 19th 2019Lawrence Feldman, MD, of the division of hematology and oncology in the department of medicine at the University of Illinois at Chicago, and a team of researchers received a grant to explore addiction, abuse, and new ways to prescribe opioids.