Tumor-Infiltrating Lymphocyte Therapy Advances Into Melanoma
Omid Hamid, MD, gives his perspective on the use of tumor-infiltrating lymphocyte therapy for patients with melanoma.
Pembrolizumab Prolongs Survival in Clear-Cell RCC
Pembrolizumab also demonstrated a disease-free survival benefit vs placebo for patients with clear-cell renal cell carcinoma.
Nanatinostat Combo Yields Responses in R/R EBV+ Peripheral T-Cell Lymphoma
Phase 2 findings support nana-val as a promising treatment option for those with EBV-positive peripheral T-cell lymphoma.
Striving for Health Care Equity by Closing the Cancer Care Gap
“If you were to ask me what the 1 magic thing would be, it would be that we would adopt a concept of 1 team, one fight nationally, and that we would be able to have our structures and our coordination of care.”
FDA Approves Pegulicianine-Based Imaging for Breast Cancer Surgery
Results from the INSITE trial support the utility of pegulicianine fluorescence-guided surgery during breast cancer surgery.
COVID-19 Pandemic Has Exacerbated CRC Surgery Disparities
Patients who are African American appeared to have worse clinical stages of colon and rectal cancer during surgery in 2020.
PET Imaging Agent Earns FDA Fast Track Designation in Recurrent Glioma
TLX101 is currently under assessment as a treatment for glioma in the IPAX-2 and IPAX-Linz studies.
Identifying Indications for Neoadjuvant Therapy in Cholangiocarcinoma
The recent Hot Topics section focuses on survival rates for patients with cholangiocarcinoma.
The Role of Molecular Profiling in Optimizing Treatment Decisions for RCC
Molecular profiling is a tool that can best determine first-line therapy options for patients with advanced RCC.
Survival Outcomes Improve With TIL Presence in TNBC
An increased TIL count in the breast tissue was associated with improved distant recurrence-free survival in patients with triple-negative breast cancer.
Increased Thyroid Cancer Risk Not Observed After Use of GLP1 Receptor Agonist
Patients who are predisposed to medullary thyroid cancer should be advised against the use of GLP1 agents.
Durvalumab Combo Yields OS Benefit in Advanced Biliary Tract Cancer
The phase 3 TOPAZ-1 trial of durvalumab plus chemotherapy showed a significant benefit vs chemotherapy alone for patients with advanced biliary tract cancer.
Learning How to Manage Immunotherapy or TKI-Related AEs in Advanced RCC
Clinicians are learning how to identify adverse effects relating to either immunotherapy or tyrosine kinase inhibitors for patients with advanced renal cell carcinoma.
Evaluation and Management of Testicular Cancer After Late Relapse
The clinical quandary by Langer et al discusses a contralateral late relapse of the original right nonseminomatous germ cell tumors.
A Multifaceted Approach to Optimizing Treatment in RCC
Moshe Ornstein, MD, discusses the heterogeneous population that comprise patients with advanced renal cell carcinoma.
Updates in Breast Cancer Care From the 41st Annual Miami Breast Cancer Conference
Several presentations from the 41st Annual Miami Breast Cancer Conference focused on new and evolving data in the space, according to Neil M. Iyengar, MD.
STARGLO Trial Meets OS End Point With Glofitamab in Relapsed/Refractory DLBCL
Additional data and results from the phase 3 STARGLO trial of glofitamab for patients with relapsed/refractory diffuse large B-cell lymphoma will be presented at an upcoming medical meeting.
Sacituzumab Tirumotecan Shows Early Efficacy in Gastric/GEJ Cancers
Sacituzumab tirumotecan elicited responses prominently in the second- and third-line and beyond setting and in those with high TROP2 expression.
Surgeons Talk Key Treatment and Institutional Advances Across Oncology Care
Experts discuss findings related to gastrointestinal cancer outcomes as well as treatment inequalities presented at the 2024 SSO Annual Meeting.
71 Utility of Performing Staging MRI in Breast Cancer Patients Over the Age of 75
Novel CAR T-Cell Therapy Yields Response in R/R Non-Hodgkin Lymphoma
HR001 was found to have an efficacious response for patients with relapsed/refractory non-Hodgkin lymphoma.
72 A Novel Biosignature for Early- Stage Invasive Breast Cancer to Predict Radiotherapy Benefit and Assess Recurrence Risk for Patients Treated With Breast- Conserving Surgery
Response Observed With Savolitinib Combo in EGFR, MET, Osimertinib-Resistant NSCLC
A proteogenomic analysis found savolitinib plus osimertinib elicited a response in patients with EGFR-mutated, MET-amplified advanced NSCLC.
COVID-19 and Chemotherapy Association Holds in Pediatric Leukemia/Lymphoma
Pediatric patients with acute lymphoblastic leukemia/lymphoma were less likely to have severe COVID-19 infection.
ODAC Approves MRD End Point in Multiple Myeloma Trials
Minimal residual disease can now be considered an end point in trials leading to accelerated approvals by the FDA for multiple myeloma.
FDA Gives Fast Track Designation to LYT-200 in Advanced Head and Neck Cancers
LYT-200 is currently being investigated for those with solid tumors and hematologic malignancies.
Olutasidenib Yields Enduring Remissions in Previously Treated IDH1+ AML
Phase 2 findings support olutasidenib as a potentially “valuable” treatment option in IDH1-mutated acute myeloid leukemia.
Microwave Ablation Shows Noninferiority to Surgery in Thyroid Cancer
Microwave ablation may be a go-to treatment option instead of surgery for patients with multifocal T1N0M0 papillary thyroid cancer.
Real-World Data Support SLNB Omission in HR+ HER2– Breast Cancer
Oncologic outcomes from a real-world analysis appear to be comparable with those observed in the sentinel lymph node biopsy arm of the SOUND trial.
Time to Screening/Treatment/Surgery is Underestimated at Breast Centers
The National Accreditation Program for Breast Centers looked at time intervals to see where delays occurred throughout the process for those with breast cancer.