More Notable Trials From SABCS 2008

Publication
Article
Oncology NEWS InternationalOncology NEWS International Vol 18 No 2
Volume 18
Issue 2
Conference|San Antonio Breast Cancer Symposium (SABCS)

Eidtmann H et al: The effect of zoledronic acid on aromatase inhibitor associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole: 36 months follow-up of ZO-FAST (abstract 44).

Eidtmann H et al: The effect of zoledronic acid on aromatase inhibitor associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole: 36 months follow-up of ZO-FAST (abstract 44).

Dowsett M et al: Risk of distant recurrence using Oncotype DX in postmenopausal primary breast cancer patients treated with anastrozole or tamoxifen: A TransATAC study (abstract 53).

Bartlett JMS et al: A prospectively planned pathology study within the TEAM trial confirms that progesterone receptor expression is prognostic but is not predictive for differential response to exemestane versus tamoxifen (abstract 81).

Articles in this issue
Consortium advances multidisciplinary program for colon cancer
Celator joins leukemia society for phase II trial of CPX-351
Genzyme nabs FDA approval for stem cell mobilizing agent
FDA launches pilot safety program for foreign drugs
Radiation oncology society adopts new moniker
Varian places RT units; offers storage system
Improvements in Pap screenings proposed
New outlook for neuroendocrine cancer
Elderly multiple myeloma patients remain responsive to novel therapy teamed with conventional treatment
Mismatched cord blood stem cells meet need for urgent Rx in acute leukemia
Risk of transplantrelated mortality doesn’t increase with cord blood
NSABP B-30: Amenorrhea relates to survival
Easy methods curtail toxins in food linked to cancer in Africa
Growth of Medicare HMOs could impact clinical trials
Trastuzumab in the adjuvant setting: Is concurrent treatment better than sequential?
Recent Videos
Thomas Powles, MBBS, MRCP, MD, highlighted fatigue, nausea, and peripheral neuropathy as toxicities observed with enfortumab vedotin plus pembrolizumab.
Large international meetings may facilitate conversations regarding disparities of care outside of high-income countries.
Updated findings from the phase 3 EV-302 trial show enduring responses and survival improvements with enfortumab vedotin plus pembrolizumab.
Additional local, regional, or national policy may bolster access to screening for colorectal cancer, according to Aasma Shaukat, MD, MPH.
Additional progression-free survival data from the phase 3 BREAKWATER trial will be presented at future meetings.
Preliminary phase 2 trial data show durvalumab plus lenalidomide was superior to durvalumab alone in refractory/advanced cutaneous T-cell lymphoma.
Performance status, age, and comorbidities may impact benefit seen with immunotherapy vs chemotherapy in patients with breast cancer.
Developing odronextamab combinations following CAR T-cell therapy failure may help elicit responses in patients with diffuse large B-cell lymphoma.
Cytokine release syndrome was primarily low or intermediate in severity, with no grade 5 instances reported among those with diffuse large B-cell lymphoma.
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