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Risk of AML in Thyroid Cancer Patients Treated With Radioactive IodineIn this interview we discuss a study that examined the risk of acute myeloid leukemia in thyroid cancer patients who have been treated with surgery and radioiodine therapy vs those treated with surgery alone.
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ColoScape Assay Can Detect Recurrence in Colorectal Cancer PatientsIn this interview, we discuss an assay that can detect disease recurrence in colorectal cancer patients.
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Clinical Decision Making in Surveillance of Non–Muscle-Invasive Bladder Cancer: The Evolving Roles of Urinary Cytology and Molecular MarkersIn this article, we discuss the requirements for development and validation of urine markers and the factors that hamper their clinical implementation. We also review current surveillance guidelines for NMIBC and provide an overview of approved urine markers for the detection and surveillance of NMIBC.
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Clinical Decision Making in Surveillance of Non–Muscle-Invasive Bladder Cancer: The Evolving Roles of Urinary Cytology and Molecular MarkersIn this article, we discuss the requirements for development and validation of urine markers and the factors that hamper their clinical implementation. We also review current surveillance guidelines for NMIBC and provide an overview of approved urine markers for the detection and surveillance of NMIBC.
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SIO President Lynda Balneaves Hopes to Continue Work on Expanding the Society’s ReachIn this interview we discuss the goals of SIO, the response to donations intended for interdisciplinary integrative health, and how palliative care and psychosocial oncology can enhance each other.
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Emergence of a Novel Staging System for Oropharyngeal Squamous Cell Carcinoma Based on HPV StatusThe staging of oropharyngeal squamous cell carcinoma has undergone key changes in the eighth edition of the American Joint Committee on Cancer Staging Manual, set to take effect January 1, 2018. We describe the revised staging parameters and the rationale in support of the changes.
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Emergence of a Novel Staging System for Oropharyngeal Squamous Cell Carcinoma Based on HPV StatusThe staging of oropharyngeal squamous cell carcinoma has undergone key changes in the eighth edition of the American Joint Committee on Cancer Staging Manual, set to take effect January 1, 2018. We describe the revised staging parameters and the rationale in support of the changes.
Latest:
Emergence of a Novel Staging System for Oropharyngeal Squamous Cell Carcinoma Based on HPV StatusThe staging of oropharyngeal squamous cell carcinoma has undergone key changes in the eighth edition of the American Joint Committee on Cancer Staging Manual, set to take effect January 1, 2018. We describe the revised staging parameters and the rationale in support of the changes.
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Radiation Dermatitis: Recognition, Prevention, and ManagementThis article highlights the typical skin reactions associated with RT, as well as current evidence-based approaches to management and intervention.
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Radiation Dermatitis: Recognition, Prevention, and ManagementThis article highlights the typical skin reactions associated with RT, as well as current evidence-based approaches to management and intervention.
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Deciding the Duration of Adjuvant Chemotherapy in a Patient With Stage III Colon Cancer: When Can Less Be More?A previously healthy 36-year-old man initially presented to his primary care physician with occasional bloody stools and dull right upper quadrant pain. Blood was sometimes mixed into his stools but was more often seen on the toilet paper after wiping.
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Optimizing Treatment Approaches in Advanced Renal CancerThis article provides a practical perspective on the management of advanced RCC, as well as insight into the current models of risk stratification and ongoing clinical trials. The discussion will focus on the currently available systemic therapies; other strategies that are beyond the scope of this article include active surveillance and metastasectomy.
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Phase II and KEYNOTE B-61: Comparative Analysis of Cancer TrialsMedical experts compare the updated results of a Phase II trial and KEYNOTE B-61, both presented at ASCO 2024, giving a comprehensive overview of these pivotal studies.
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Treatment of HIV-Associated Lymphomas: The Latest Approaches for Optimizing OutcomesIn those with DLBCL, Burkitt lymphoma, and Hodgkin lymphoma, cure is often achieved. Furthermore, in the salvage setting, whether auto-HCT or allo-HCT is used, the same appears to be true. A great deal of progress has been made in the treatment of lymphoma in patients with HIV infection, but more remains to be done before outcomes are comparable to those of the general population.
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Treatment of HIV-Associated Lymphomas: The Latest Approaches for Optimizing OutcomesIn those with DLBCL, Burkitt lymphoma, and Hodgkin lymphoma, cure is often achieved. Furthermore, in the salvage setting, whether auto-HCT or allo-HCT is used, the same appears to be true. A great deal of progress has been made in the treatment of lymphoma in patients with HIV infection, but more remains to be done before outcomes are comparable to those of the general population.
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Adding Nivolumab to Induction Chemotherapy Safe in Younger AML PatientsThis video highlights a phase II trial that tested the addition of nivolumab to combination induction chemotherapy of cytarabine and idarubicin for patients with newly diagnosed acute myeloid leukemia.
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Skin Lesions in Patient With Metastatic Breast CancerA 57-year-old woman with metastatic HER2/neu-positive breast cancer started treatment with a combination of docetaxel, pertuzumab, and trastuzumab. On the fourth cycle the patient complained of mild irritation and a skin rash on her left upper extremity. What is your diagnosis?
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Is Molecular Remission the Goal When Treating Myeloma?In this interview we discuss the goals of therapy in multiple myeloma, treatment combinations and transplantation, and how markers such as minimal residual disease are used.
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DLBCL Trials May Exclude Patients Who Need Novel Therapies MostIn this interview we discuss how a short diagnosis-to-treatment interval in newly diagnosed diffuse large B-cell lymphoma is associated with worse outcomes and how this could lead to trials favoring patients with a longer diagnosis-to-treatment interval and better expected outcomes.
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Precision Imaging in Breast CancerThis video highlights four posters from SABCS on the use of mammography, magnetic resonance imaging, and radiomics as biomarkers for treatment response.
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Clinical Pearls for Community Oncologists Treating MyelofibrosisThe panel closes their discussion on myelofibrosis treatment updates by sharing clinical pearls for community oncologists.
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Preventing, Treating Relapse After ASCT in Hematologic Malignancy PatientsThis video highlights research into the use of post-transplant therapies to prevent or treat disease recurrence following allogeneic stem cell transplantation.
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Identifying Children With Leukemia Predisposition SyndromesThis video reviews classic syndromes associated with increased leukemia susceptibility and highlights pediatric patients who may be at increased risk for an inherited leukemia predisposition and should receive additional work-up.
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Immunotherapies Could Play Role in CALR-Positive Myeloproliferative NeoplasmsThis video highlights a study that establishes mutated CALR as a myeloproliferative neoplasms–specific tumor antigen and provides a rationale for the development of immunotherapies targeting mutated CALR.
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Could Single-Cell RNA Sequencing Help Personalize Multiple Myeloma Treatment?This video highlights research that found that single-cell RNA sequencing can better characterize patients and potentially improve multiple myeloma treatment in a more personalized manner.
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Expert Insight and Future Perspectives for Follicular LymphomaPanelists close the discussion by offering insights and future perspectives on the treatment landscape for follicular lymphoma.
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Novel Treatment Approaches in Higher-Risk Myelodysplastic SyndromesThis video reviews novel treatment approaches in the management of higher-risk myelodysplastic syndromes.
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Predicting Response to Immunotherapy With a Mathematical ModelIn this interview, we discuss a mathematical model that was created to predict patient response to immunotherapy for cancer treatment.
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Predicting Response to Immunotherapy With a Mathematical ModelIn this interview, we discuss a mathematical model that was created to predict patient response to immunotherapy for cancer treatment.
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POINT: Weighing the Risks and Benefits of Neoadjuvant Therapy in Resectable Pancreatic CancerASCO clinical practice guidelines recommend resection followed by treatment with gemcitabine and capecitabine as the standard of care; however, neoadjuvant therapy is also considered an appropriate alternative.
