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Nonoperative Management of Rectal Cancer: A Modern PerspectiveIn this article, we provide a summary of nonoperative management of locally advanced rectal cancer in the modern era. Our focus is on technical details of tumor response and patient assessment after chemoradiotherapy, as well as a review of existing clinical data.
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Nonoperative Management of Rectal Cancer: A Modern PerspectiveIn this article, we provide a summary of nonoperative management of locally advanced rectal cancer in the modern era. Our focus is on technical details of tumor response and patient assessment after chemoradiotherapy, as well as a review of existing clinical data.
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POINT: Early Salvage vs Adjuvant Radiotherapy for High-Risk Prostate CancerSerial PSA testing with early salvage radiotherapy is a viable option in most high-risk men.
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COUNTERPOINT: Early Salvage vs Adjuvant Radiotherapy for High-Risk Prostate CancerThe data for adjuvant radiotherapy remain strong.
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Which Drug Is Contraindicated in RVD-Treated Multiple Myeloma Patients?Do you know when to switch treatment combinations or stop certain treatments altogether in the management of patients with multiple myeloma? Take part in a series of case scenarios and see if you can pick the correct course of action for each in our latest quiz.
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Pneumonitis From Anti–PD-1/ PD-L1 TherapyWhile the incidence of irAEs is relatively low, the absolute number of patients receiving immune checkpoint inhibitors is steadily increasing. Thus, it is likely that, with time, larger numbers of patients will develop irAEs, including pneumonitis.
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Pancreatic Neuroendocrine Tumors: State-of-the-Art Diagnosis and ManagementIn this review, we focus on the treatment of well-differentiated early and metastatic PNETs, emphasizing current controversies, recent advances in therapy, and the multidisciplinary approach required for optimal treatment.
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Early Palliative Care Improves QOL for Lung and GI Cancer PatientsThe early integration of oncology and palliative care enhanced coping strategies and improved QOL for patients newly diagnosed with incurable lung or GI cancer.
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Radiation Oncologist Speaks to AI Potential in the Cancer SpaceRichard Bakst, MD, speaks to the potential use of artificial intelligence in the radiation oncology space, and how he hopes to see it evolve.
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RT for Breast Cancer Patients Is 'Less Scary' Than AnticipatedThis video examines patient fears and misconceptions regarding radiation therapy for the treatment of breast cancer.
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Optimal Therapies for Metastatic Hormone-Sensitive Prostate CancerIn this interview we discuss the STOPCaP trial, a meta-analysis that looked at optimal systemic therapy options for men with metastatic hormone-sensitive prostate cancer.
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Genetic Variants Could Predict Cancer's Resistance to Radiation TherapyThis video highlights a large-scale profiling effort that seeks to identify and classify mutant alleles driving resistance to radiation therapy across different cancer types.
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Mucosal Melanoma: New Insights and Therapeutic Options for a Unique and Aggressive DiseaseHere, we review the features of mucosal melanoma that distinguish it from melanomas arising at other sites, and we highlight recent biological discoveries and emerging treatment options for this aggressive disease.
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Mucosal Melanoma: New Insights and Therapeutic Options for a Unique and Aggressive DiseaseHere, we review the features of mucosal melanoma that distinguish it from melanomas arising at other sites, and we highlight recent biological discoveries and emerging treatment options for this aggressive disease.
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Mucosal Melanoma: New Insights and Therapeutic Options for a Unique and Aggressive DiseaseHere, we review the features of mucosal melanoma that distinguish it from melanomas arising at other sites, and we highlight recent biological discoveries and emerging treatment options for this aggressive disease.
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The Developing Role of Anti–Epidermal Growth Factor Receptor Agents in the Treatment of Advanced or Metastatic Colorectal CancerAnti-EGFR therapy is a valuable addition to the armamentarium of treatment options for patients with metastatic colorectal cancer. However, RAS mutation status is an imperfect biomarker for prediction of therapeutic outcomes in this setting. The recent discovery of tumor sidedness as a predictor of response highlights how little we understand about which patients are the most appropriate to receive drugs that target EGFR.
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Radical Prostatectomy for Patients With Oligometastatic Prostate CancerIn this review, we will examine the theories supporting treatment to achieve local disease control in oligometastatic prostate cancer, analyze the evidence supporting cytoreductive prostatectomy, and review selected relevant ongoing clinical trials.
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Radical Prostatectomy for Patients With Oligometastatic Prostate CancerIn this review, we will examine the theories supporting treatment to achieve local disease control in oligometastatic prostate cancer, analyze the evidence supporting cytoreductive prostatectomy, and review selected relevant ongoing clinical trials.
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Radical Prostatectomy for Patients With Oligometastatic Prostate CancerIn this review, we will examine the theories supporting treatment to achieve local disease control in oligometastatic prostate cancer, analyze the evidence supporting cytoreductive prostatectomy, and review selected relevant ongoing clinical trials.
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Strategies for Addressing Cancer Patients’ Complaints of FatigueCancer-related fatigue is a common, albeit complex, symptom experienced by many cancer patients. Identification of fatigue and assessment of its severity should be a part of routine office care and can be performed using simple, one-question screening tools.
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Strategies for Addressing Cancer Patients’ Complaints of FatigueCancer-related fatigue is a common, albeit complex, symptom experienced by many cancer patients. Identification of fatigue and assessment of its severity should be a part of routine office care and can be performed using simple, one-question screening tools.
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Strategies for Addressing Cancer Patients’ Complaints of FatigueCancer-related fatigue is a common, albeit complex, symptom experienced by many cancer patients. Identification of fatigue and assessment of its severity should be a part of routine office care and can be performed using simple, one-question screening tools.
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PI3K Inhibitors: Understanding Toxicity Mechanisms and ManagementHere, we briefly describe the clinical efficacy of PI3K inhibitors, then discuss the mechanisms and management of the more common unusual toxicities seen with these agents.
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Unmet Needs in Diffuse Large B-Cell LymphomaAndre H. Goy, MD, and Andrew Ip, MD, offer closing remarks on unmet needs in the treatment of diffuse large B-cell lymphoma.
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POINT-Which Treatment Modality for Localized Prostate Cancer Yields Superior Quality of Life: Radiotherapy or Prostatectomy?Quality of life is better after modern radiotherapy compared with surgery.
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Breast Lesion in Patient With HIVA 41-year-old woman with a past medical history notable for HIV underwent her first screening mammogram, which demonstrated a 1.5-cm irregular focal asymmetry in the left breast. What is your diagnosis?
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Hypofractionated Regimen Safe, Feasible in Elderly Bladder Cancer PatientsIn this interview we discuss results of the HYBRID trial, which tested a hypofractionated regimen of 36 Gy over six fractions in elderly muscle-invasive bladder cancer patients who were ineligible for standard treatments.
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ctDNA Predicts Outcomes in Lung Cancer Patients Receiving Radiation TherapyThis peer-to-peer exchange highlights results of a study that tested whether analyzing circulating tumor DNA (ctDNA) during treatment with chemoradiotherapy could predict outcomes in patients with localized lung cancer.
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ctDNA Predicts Outcomes in Lung Cancer Patients Receiving Radiation TherapyThis peer-to-peer exchange highlights results of a study that tested whether analyzing circulating tumor DNA (ctDNA) during treatment with chemoradiotherapy could predict outcomes in patients with localized lung cancer.
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Endings & Beginnings-Grief, Loss, and Letting GoAs an oncology health care provider, it is crucially important to process grief and loss in order to best care for yourself and your patients.
