Authors
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Favorable Results Seen With APX005M in Combination Therapy for Metastatic Ductal Pancreatic AdenocarcinomaCancer Network spoke with Mark H. O'Hara, MD, about the safety and efficacy of APX005M in combination with standard chemotherapy with or without nivolumab.
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Does Tumor Biology Play a Role in Colon Cancer Racial Disparities?Cancer Network spoke with Jennie Williams, PhD, and Jenny Paredes, a PhD student, about how tumor biology impacts chemotherapy response in African American vs Caucasian patients.
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Breast Cancer Screening Can Begin Later in Childhood Cancer SurvivorsResearch evaluated whether initiating breast cancer screening at age 30 may be preferable to current guidelines among survivors of childhood cancer with a history of chest irradiation.
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Dr. Schmidt on AMAROS Trial Results: Radiotherapy vs Surgery of the Axilla in Breast CancerCancer Network spoke with Hank Schmidt, MD, about the 10-year follow-up results of the EORTC AMAROS trial of radiotherapy vs surgery of the axilla in breast cancer patients with a positive sentinel node.
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CheckMate 204: New First-Line Therapy for Asymptomatic Melanoma Brain Metastases?The results of the phase II trial examining combination immunotherapy were presented during the ASCO 2019 meeting.
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Can Social and Environmental Factors Cause Cancer Disparities?Cancer Network spoke with Dr. Scarlett Lin Gomez about the role gender, socioeconomic status, race/ethnicity, and neighborhood characteristics have on health outcomes in cancer.
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Non–Small-Cell Lung Cancer After Mantle Radiation: A Case Report and Brief ReviewIn this case report, we present a non-Hodgkin lymphoma survivor who was incidentally found to have non–small-cell lung cancer 30 years after undergoing treatment that included mantle radiation. We discuss the treatment-related risk factors for lung cancer in this population and potential implications for long-term follow-up.
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The Role of Primary Tumor Treatment and Metastasis-Directed Therapy in Oligometastatic Prostate CancerThis case looks at an otherwise healthy 59-year-old man who was recently diagnosed with clinical stage IVB prostate adenocarcinoma. What is the most appropriate management for this patient?
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Pneumocystis jirovecii Pneumonia in Patients With Metastatic Prostate Cancer on Corticosteroids for Malignant Spinal Cord Compression: Two Case Reports and a Guideline ReviewTwo case reports and a review of PCP in patients with solid tumors.
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The Role of Primary Tumor Treatment and Metastasis-Directed Therapy in Oligometastatic Prostate CancerThis case looks at an otherwise healthy 59-year-old man who was recently diagnosed with clinical stage IVB prostate adenocarcinoma. What is the most appropriate management for this patient?
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When Surgery Is Not an Option in Renal Cell Carcinoma: The Evolving Role of Stereotactic Body Radiation TherapyThis review summarizes the current evidence supporting the use of SBRT as treatment for inoperable renal cell carcinoma, as well as provides recommendations for patient selection and reviews the technical aspects of treatment and the expected toxicities.
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Overcoming Physical and Social Barriers in the Lymphoma FieldLeaders from the lymphoma space highlight the importance of mentorship in establishing their careers and impart advice to women looking to advance theirs.
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Evaluating Immunotherapy in Nonmetastatic Colorectal CancerDr. Sinicrope reviews the phase III ATOMIC trial, which is testing standard chemotherapy alone or in combination with the anti–PD-L1 antibody atezolizumab as adjuvant therapy in a subset of colon cancer patients.
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Dr. Oratz on PARP Inhibitors to Treat Patients With Breast CancerCancer Network spoke with Ruth Oratz, MD, a medical oncologist at NYU Langone Perlmutter Cancer Center in New York City, about the use of PARP inhibitors for breast cancer.
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Using Cannabis as a Palliative Treatment in Patients With CancerAhead of the ASCO Annual Meeting, we discuss the use of cannabis as a palliative treatment in patients with cancer with Claude Cyr, MD.
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Managing Cytokine Release Syndrome in Patients on CAR T-Cell TherapyAhead of the ASCO Annual Meeting, we discuss the assessment and management of cytokine release syndrome in patients with cancer with Elizabeth Shpall, MD.
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Considerations When Initiating Neratinib for Breast Cancer: How to Prevent and Treat DiarrheaAn oncology pharmacist discusses how to prevent and treat diarrhea in patients taking neratinib for breast cancer.
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Point: Should Active Surveillance Be Used for Gleason 3+4 Prostate Cancer?In this Point/Counterpoint, Drs. Bhat and Punnen argue that active surveillance can be beneficial for patients with intermediate-risk prostate cancer.
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Point: Should Active Surveillance Be Used for Gleason 3+4 Prostate Cancer?In this Point/Counterpoint, Drs. Bhat and Punnen argue that active surveillance can be beneficial for patients with intermediate-risk prostate cancer.
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Counterpoint: Should Active Surveillance Be Used for Gleason 3+4 Prostate Cancer?In this Point/Counterpoint, Drs. Madueke and Abern argue that active surveillance should not currently be considered for patients with intermediate-risk prostate cancer.
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Breaking New Ground in the Treatment of Advanced Endometrial CancerDr. Makker summarizes the standard of care for the treatment of advanced endometrial cancer, with a look forward to the multitude of clinical trials evaluating novel therapy combinations that are currently enrolling patients or underway.
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Suicide in Patients With Cancer: Identifying the Risk FactorsThis article reviews the prevalence of suicide in patients with cancer, risk factors, related conditions, and interventions to identify and treat suicidal patients.
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Suicide in Patients With Cancer: Identifying the Risk FactorsThis article reviews the prevalence of suicide in patients with cancer, risk factors, related conditions, and interventions to identify and treat suicidal patients.
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Personality Disorders in Patients with CancerPersonality disorders become exacerbated under stressful cancer-related situations and may lead to adverse consequences and outcomes.
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Suicide in Patients With Cancer: Identifying the Risk FactorsThis article reviews the prevalence of suicide in patients with cancer, risk factors, related conditions, and interventions to identify and treat suicidal patients.
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Preventing Gastric Cancer Development by Inhibiting the Virulence of H. pylori InfectionDr. Wilson discusses a chemopreventive drug that may help prevent gastric cancer by acting directly on H. pylori.
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Progressive Red-to-Violaceous Papules and Plaques on the Neck and Abdominal Skin of a 70-Year-Old WomanA 70-year-old woman developed red-to-violaceous papules, plaques, and nodule- like skin lesions several months prior to her presentation. The skin lesions mostly involved her lower neck and abdominal area. What is the most likely diagnosis?
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Evolving Strategies for the Management of BRAF-Mutant Metastatic Colorectal CancerIn this article, we review the characteristics of the BRAF mutation and the evolving strategies for managing BRAF-mutant metastatic colorectal cancer.
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Clinical Trials in Progress: COBRAPhase 2/3 Study of Circulating Tumor DNA as a Predictive Biomarker in Adjuvant Chemotherapy in Patients With Stage IIA Colon Cancer (COBRA): a first-in-kind trial seeks to provide level 1 evidence in evaluating the role of ctDNA as a guide for clinicians in the decision to administer adjuvant chemotherapy to patients with stage IIA colon cancer (NRG GI-005) (NCT04068103).
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Evolving Strategies for the Management of BRAF-Mutant Metastatic Colorectal CancerIn this article, we review the characteristics of the BRAF mutation and the evolving strategies for managing BRAF-mutant metastatic colorectal cancer.
