Breakthroughs in Therapeutic Options for Relapsed/Refractory Multiple Myeloma

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EP: 1.Breakthroughs in Therapeutic Options for Relapsed/Refractory Multiple Myeloma

EP: 2.Highlights From the 2021 European Hematology Association Congress on Multiple Myeloma

EP: 3.Upcoming Abstracts on Multiple Myeloma for Presentation at 2021 ASH

EP: 4.Biggest FDA News for Multiple Myeloma in 2021

EP: 5.Treatment Options for Transplant-Eligible Multiple Myeloma

EP: 6.Treatment Options for Transplant-Ineligible Multiple Myeloma

EP: 7.Navigating Individual Treatment for Relapsed/Refractory Multiple Myeloma

EP: 8.Understanding Adverse Events in Multiple Myeloma

EP: 9.BCMA-Directed Agents for Multiple Myeloma

EP: 10.Optimal Therapies for Relapsed/Refractory Multiple Myeloma

EP: 11.Emerging Research and Therapies for Multiple Myeloma

EP: 12.Upcoming Phase 3 Data in Multiple Myeloma

EP: 13.Trials Evaluating Emerging Maintenance Therapy Regimens in Multiple Myeloma

EP: 14.Looking Ahead to the Future of Multiple Myeloma Treatment

EP: 15.Current Leading Therapies for Multiple Myeloma

Nina Shah, MD: One of the biggest breakthroughs that we've had for multiple myeloma is the first FDA-approved engineered T-cell therapy. It happened midway through the year in the spring, giving us the approval for the bb2121 product, also known as ide-cel [idecabtagene vicleucel; Abecma], for patients with relapsed or refractory multiple myeloma [after 4 or more prior lines of therapy]. That's probably the biggest breakthrough but we've also had some interesting other breakthroughs, which include approvals of certain forms of daratumumab (Darzalex), for example, the subcutaneous form, in conjunction with carfilzomib (Kyprolis) and dexamethasone for relapsed or refractory disease in [patients who received] 1 to 3 prior lines [of therapy]. Similarly, isatuximab (Sarclisa), carfilzomib, and dexamethasone has also been approved. We have a lot more options for our patients in the relapsed or refractory setting.