Highlights From the 2021 European Hematology Association Congress on Multiple Myeloma

EP: 1.Breakthroughs in Therapeutic Options for Relapsed/Refractory Multiple Myeloma

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EP: 2.Highlights From the 2021 European Hematology Association Congress on Multiple Myeloma

EP: 3.Upcoming Abstracts on Multiple Myeloma for Presentation at 2021 ASH

EP: 4.Biggest FDA News for Multiple Myeloma in 2021

EP: 5.Treatment Options for Transplant-Eligible Multiple Myeloma

EP: 6.Treatment Options for Transplant-Ineligible Multiple Myeloma

EP: 7.Navigating Individual Treatment for Relapsed/Refractory Multiple Myeloma

EP: 8.Understanding Adverse Events in Multiple Myeloma

EP: 9.BCMA-Directed Agents for Multiple Myeloma

EP: 10.Optimal Therapies for Relapsed/Refractory Multiple Myeloma

EP: 11.Emerging Research and Therapies for Multiple Myeloma

EP: 12.Upcoming Phase 3 Data in Multiple Myeloma

EP: 13.Trials Evaluating Emerging Maintenance Therapy Regimens in Multiple Myeloma

EP: 14.Looking Ahead to the Future of Multiple Myeloma Treatment

EP: 15.Current Leading Therapies for Multiple Myeloma

Nina Shah, MD: One of the major highlights from the European Hematology Association Congress from 2021, particularly for multiple myeloma, was the presentation of the overall survival data from the MAIA trial [NCT02252172]. In this trial, patients with newly diagnosed multiple myeloma who were transplant-ineligible were randomized to receive daratumumab (Darzalex), lenalidomide (Revlimid), and dexamethasone versus lenalidomide and dexamethasone with a primary end point of PFS [progression-free survival]. We already knew that the patients did better from a PFS standpoint [if they] got the triplet therapy. Finally, we now have overall survival data, and that data look nice for these patients who are transplant ineligible and who may be getting daratumumab, lenalidomide, and dexamethasone. They had a significant overall survival improvement versus lenalidomide and dexamethasone. That was one of the biggest takeaways from that Congress because it makes you feel better about choosing that regimen and has changed the way that a lot of us approach transplant-ineligible multiple myeloma.