Following recent data from the ADRIATIC study, the Oncology Brothers and Eric Singhi, MD, discuss the role of prophylactic cranial irradiation (PCI) in patients with small cell lung cancer.
CID-078 Earns FDA Orphan Drug Designation in Small Cell Lung Cancer
Developers have initiated a phase 1 clinical trial evaluating the safety, tolerability, and early antitumor activity of CID-078 in advanced solid tumors.
Practice-Changing Lung Cancer Data From The 2025 ASCO Annual Meeting
Stephen Liu, MD, and Joshua Sabari, MD, discuss the most intriguing non–small cell lung cancer and small cell lung cancer breakthroughs from the meeting.
Lurbinectedin Maintenance Combo Earns FDA Priority Review in ES-SCLC
The FDA has set a Prescription Drug User Fee Act date of October 7, 2025, for its decision on approving the lurbinectedin combination in this SCLC population.
Considering Dosing and AE Management Strategies With Tarlatamab in SCLC
Experts from Washington University in St. Louis discuss prior data and strategies for mitigating toxicities like CRS associated with tarlatamab in SCLC.
Second-Line Tarlatamab Improves PFS, OS in Small Cell Lung Cancer
Data from DeLLphi-304 support tarlatamab as a preferable second-line therapy for patients with small cell lung cancer.
Novel CAR T-cell Therapy Shows Best Overall PR in R/R SCLC and LCNEC
Safety and efficacy were noted with LB2102 for patients with small cell lung cancer and large cell neuroendocrine carcinoma.